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topic_facet:"EC 1.14.14.1"
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PubPharm (18)
1
Evaluation of the drug-drug interaction potential of brigatinib using a physiologically-based pharmacokinetic modeling approach
enthalten in:
CPT: pharmacometrics & systems pharmacology
| 2024
von
Hanley, M.
|
Yeo, K.
|
Tugnait, M.
| +5
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2
Risk assessment of drug-drug interaction potential for bintrafusp alfa with cytochrome P4503A4 substrates : A totality of evidence approach
enthalten in:
Clinical and translational science
| 2022
von
Vugmeyster, Y.
|
Locke, G.
|
Helwig, C.
| +3
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3
Current Practices, Gap Analysis, and Proposed Workflows for PBPK Modeling of Cytochrome P450 Induction : An Industry Perspective
enthalten in:
Clinical pharmacology and therapeutics
| 2022
von
Hariparsad, N.
|
Ramsden, D.
|
Taskar, K.
| +20
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4
Alternatives to rifampicin : A review and perspectives on the choice of strong CYP3A inducers for clinical drug-drug interaction studies
enthalten in:
Clinical and translational science
| 2022
von
Bolleddula, J.
|
Gopalakrishnan, S.
|
Hu, P.
| +2
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5
Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2020
von
Pusalkar, S.
|
Zhou, X.
|
Li, Y.
| +8
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6
Effects of Strong CYP2C8 or CYP3A Inhibition and CYP3A Induction on the Pharmacokinetics of Brigatinib, an Oral Anaplastic Lymphoma Kinase Inhibitor, in Healthy Volunteers
enthalten in:
Clinical pharmacology in drug development
| 2020
von
Tugnait, M.
|
Gupta, N.
|
Hanley, M.
| +5
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7
Effects of Strong CYP3A Inhibition and Induction on the Pharmacokinetics of Ixazomib, an Oral Proteasome Inhibitor : Results of Drug-Drug Interaction Studies in Patients With Advanced Solid Tumors or Lymphoma and a Physiologically Based Pharmacokinetic Analysis
enthalten in:
Journal of clinical pharmacology
| 2018
von
Gupta, N.
|
Hanley, M.
|
Venkatakrishnan, K.
| +13
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8
Should Race-Genotype Interactions Be Considered in the Global Development of CYP2C19 Substrates? A Proposed Framework Using Physiologically Based Pharmacokinetic Modeling
enthalten in:
Journal of clinical pharmacology
| 2017
von
Patel, C.
|
Rathi, C.
|
Venkatakrishnan, K.
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9
Mechanism of cytochrome P450-3A inhibition by ketoconazole
enthalten in:
The Journal of pharmacy and pharmacology
| 2011
von
Greenblatt, D.
|
Zhao, Y.
|
Venkatakrishnan, K.
| +5
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10
Sources of variability in ketoconazole inhibition of human cytochrome P450 3A in vitro
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2010
von
Greenblatt, D.
|
Venkatakrishnan, K.
|
Harmatz, J.
| +2
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Thema: EC 1.14.14.1
Medienart
18
Aufsätze
10
E-Artikel
10
E-Ressourcen
8
Gedruckte Aufsätze
Zeitschriftentitel
5
Drug metabolism and disposition: the biological...
2
Clinical and translational science
2
Clinical pharmacology and therapeutics
2
Journal of clinical pharmacology
1
Biopharmaceutics & drug disposition
1
CPT: pharmacometrics & systems pharmacology
1
Clinical pharmacokinetics
1
Clinical pharmacology in drug development
1
The Journal of pharmacology and experimental th...
1
The Journal of pharmacy and pharmacology
1
Xenobiotica; the fate of foreign compounds in b...
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Thema
EC 1.14.14.1
17
Journal Article
13
Cytochrome P-450 CYP3A
7
Cytochrome P-450 CYP3A Inhibitors
5
9035-51-2
5
Cytochrome P-450 Enzyme System
5
Research Support, Non-U.S. Gov't
4
Comparative Study
4
Cytochrome P-450 CYP2D6
4
Cytochrome P-450 CYP3A Inducers
4
Enzyme Inhibitors
4
Rifampin
4
VJT6J7R4TR
3
CYP3A protein, human
3
Ketoconazole
3
Pyrimidines
3
R9400W927I
3
Randomized Controlled Trial
3
Research Support, U.S. Gov't, P.H.S.
3
Review
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Erscheinungszeitraum
6
2020-
4
2010-2019
8
2000-2009
Erscheinungsjahr(e)
Von:
Bis:
Sprache
18
Englisch
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