Suchergebnisse - "PAR-1"

PubPharm (205)

1

Discovery of Potent and Selective Quinoxaline-Based Protease-Activated Receptor 4 (PAR4) Antagonists for the Prevention of Arterial Thrombosis

enthalten in: Journal of medicinal chemistry | 2024

von Zhang, X. | Jiang, W. | Richter, J. | +21

2

The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes

enthalten in: The Journal of clinical investigation | 2023

von Denorme, F. | Armstrong, N. | Stoller, M. | +19

CommentIn: J Clin Invest. 2023 Sep 15;133(18):. - PMID 37712423

3

Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis

enthalten in: Arteriosclerosis, thrombosis, and vascular biology | 2023

von Li, S. | Wang, W. | Lin, L. | +8

4

An optimized agonist peptide of protease-activated receptor 4 and its use in a validated platelet-aggregation assay

enthalten in: Platelets | 2022

von Yang, J. | Mapelli, C. | Wang, Z. | +5

5

The PAR4 Platelet Thrombin Receptor Variant rs773902 does not Impact the Incidence of Thrombotic or Bleeding Events in a Healthy Older Population

enthalten in: Thrombosis and haemostasis | 2022

von Selvadurai, M. | Riaz, M. | Xie, S. | +4

6

Discovery of Two Novel Antiplatelet Clinical Candidates (BMS-986120 and BMS-986141) That Antagonize Protease-Activated Receptor 4

enthalten in: Journal of medicinal chemistry | 2022

von Priestley, E. | Banville, J. | Deon, D. | +30

7

Human and mouse PAR4 are functionally distinct receptors : Studies in novel humanized mice

enthalten in: Journal of thrombosis and haemostasis : JTH | 2022

von Renna, S. | Michael, J. | Kong, X. | +5

8

C1-inhibitor influence on platelet activation by thrombin receptors agonists

enthalten in: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis | 2022

von Tarandovskiy, I. | Buehler, P. | Karnaukhova, E.

9

PAR4-Mediated PI3K/Akt and RhoA/ROCK Signaling Pathways Are Essential for Thrombin-Induced Morphological Changes in MEG-01 Cells

enthalten in: International journal of molecular sciences | 2022

von Heo, Y. | Jeon, H. | Namkung, W.

10

Protease Activated Receptors and Arthritis

enthalten in: International journal of molecular sciences | 2021

von Lucena, F. | McDougall, J.

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