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PubPharm (15)
1
Identification of positive modulators of TRPM5 channel from a high-throughput screen using a fluorescent membrane potential assay
enthalten in:
SLAS discovery : advancing life sciences R & D
| 2022
von
Virginio, C.
|
Aldegheri, L.
|
Nola, S.
| +6
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2
From High-Throughput Screening to Target Validation : Benzo[d]isothiazoles as Potent and Selective Agonists of Human Transient Receptor Potential Cation Channel Subfamily M Member 5 Possessing In Vivo Gastrointestinal Prokinetic Activity in Rodents
enthalten in:
Journal of medicinal chemistry
| 2021
von
Barilli, A.
|
Aldegheri, L.
|
Bianchi, F.
| +14
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3
Pharmacological characterisation of MDI-222, a novel AMPA receptor positive allosteric modulator with an improved safety profile
enthalten in:
Journal of psychopharmacology (Oxford, England)
| 2020
von
Ward, S.
|
Harries, M.
|
Aldegheri, L.
| +10
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4
A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons
enthalten in:
The Journal of pharmacology and experimental therapeutics
| 2015
von
Rosato-Siri, M.
|
Zambello, E.
|
Mutinelli, C.
| +7
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5
Optimisation of an integrated approach for cardiac safety profiling of novel compounds
enthalten in:
Journal of pharmacological and toxicological methods
| 2013
von
Cunego, L.
|
Philip, D.
|
Bertani, S.
| +9
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6
Integration of lead optimization with crystallography for a membrane-bound ion channel target : discovery of a new class of AMPA receptor positive allosteric modulators
enthalten in:
Journal of medicinal chemistry
| 2011
von
Ward, S.
|
Harries, M.
|
Aldegheri, L.
| +17
ErratumIn: J Med Chem. 2011 Jan 13;54(1):93
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7
Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators
enthalten in:
Journal of medicinal chemistry
| 2011
von
Ward, S.
|
Harries, M.
|
Aldegheri, L.
| +17
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8
N-substituted pyrrolidines and tetrahydrofurans as novel AMPAR positive modulators
enthalten in:
Bioorganic & medicinal chemistry letters
| 2010
von
Thewlis, K.
|
Aldegheri, L.
|
Harries, M.
| +3
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9
Discovery of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a novel clinical AMPA receptor positive modulator
enthalten in:
Journal of medicinal chemistry
| 2010
von
Ward, S.
|
Harries, M.
|
Aldegheri, L.
| +18
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10
Discovery of N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a Novel Clinical AMPA Receptor Positive Modulator
enthalten in:
Journal of medicinal chemistry
| 2010
von
Ward, S.
|
Harries, M.
|
Aldegheri, L.
| +18
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Zeitschriftentitel
5
Journal of medicinal chemistry
2
European journal of pharmacology
2
Neuroscience letters
1
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1
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1
SLAS discovery : advancing life sciences R & D
1
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1
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Thema
9
Journal Article
4
Receptors, AMPA
3
Recombinant Proteins
2
Pyrrolidines
2
Research Support, Non-U.S. Gov't
2
Sulfonamides
2
TRPM Cation Channels
1
01K63SUP8D
1
66-40-0
1
AMPA receptor
1
Antidepressive Agents, Second-Generation
1
Automated patch clamp
1
Benzothiazoles
1
Blood Proteins
1
Calcium
1
Cell-based assay
1
Chrna7 protein, rat
1
Clinical Trial, Phase I
1
Comparative Study
1
ERG1 Potassium Channel
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Erscheinungszeitraum
14
2000-
1
1900-1999
Erscheinungsjahr(e)
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Sprache
9
Englisch
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