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topic_facet:"Poly(ADP-ribose) Polymerase Inhibitors"
topic_facet:"Research Support, Non-U.S. Gov't"
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PubPharm (30)
1
Targeting the DNA damage response for cancer therapy
enthalten in:
Biochemical Society transactions
| 2023
von
Curtin, N.
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2
Repositioning PARP inhibitors for SARS-CoV-2 infection(COVID-19); a new multi-pronged therapy for acute respiratory distress syndrome?
enthalten in:
British journal of pharmacology
| 2020
von
Curtin, N.
|
Bányai, K.
|
Thaventhiran, J.
| +3
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3
Evaluating the potential of kinase inhibitors to suppress DNA repair and sensitise ovarian cancer cells to PARP inhibitors
enthalten in:
Biochemical pharmacology
| 2019
von
Mukhopadhyay, A.
|
Drew, Y.
|
Matheson, E.
| +4
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4
Strategies Employed for the Development of PARP Inhibitors
enthalten in:
Methods in molecular biology (Clifton, N.J.)
| 2017
von
Canan, S.
|
Maegley, K.
|
Curtin, N.
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5
Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer
enthalten in:
British journal of cancer
| 2016
von
Drew, Y.
|
Ledermann, J.
|
Hall, G.
| +14
CommentIn: Br J Cancer. 2016 Mar 29;114(7):713-5. - PMID 27022824
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6
PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia
enthalten in:
Oncotarget
| 2015
von
Herriott, A.
|
Tudhope, S.
|
Junge, G.
| +13
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7
Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System
enthalten in:
Molecular cancer therapeutics
| 2015
von
Parrish, K.
|
Cen, L.
|
Murray, J.
| +11
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8
Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma
enthalten in:
Current opinion in oncology
| 2014
von
Vormoor, B.
|
Curtin, N.
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9
Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies
enthalten in:
Haematologica
| 2013
von
Gaymes, T.
|
Mohamedali, A.
|
Patterson, M.
| +8
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10
A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation
enthalten in:
Cancer chemotherapy and pharmacology
| 2013
von
Plummer, R.
|
Lorigan, P.
|
Steven, N.
| +10
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Thema: Poly(ADP-ribose) Polymerase Inhibitors
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Thema: Research Support, Non-U.S. Gov't
Medienart
30
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Thema
30
Journal Article
Poly(ADP-ribose) Polymerase Inhibitors
Research Support, Non-U.S. Gov't
15
Enzyme Inhibitors
14
EC 2.4.2.30
13
Antineoplastic Agents
12
Poly(ADP-ribose) Polymerases
10
7GR28W0FJI
10
Dacarbazine
10
Indoles
10
Temozolomide
10
YF1K15M17Y
9
8237F3U7EH
9
rucaparib
7
12794-10-4
7
Benzodiazepines
6
1-(4-dimethylaminomethylphenyl)-8,9-dihydro-7H-...
6
Azulenes
6
Poly (ADP-Ribose) Polymerase-1
5
PARP1 protein, human
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Erscheinungszeitraum
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2020-
15
2010-2019
13
2000-2009
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