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topic_facet:"Poly(ADP-ribose) Polymerase Inhibitors"
topic_facet:"Poly(ADP-ribose) Polymerases"
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PubPharm (19)
1
Poly(ADP-ribose) polymerase inhibition : past, present and future
enthalten in:
Nature reviews. Drug discovery
| 2020
von
Curtin, N.
|
Szabo, C.
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2
Poly(ADP-Ribose) Polymerase in Cervical Cancer Pathogenesis : Mechanism and Potential Role for PARP Inhibitors
enthalten in:
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
| 2016
von
Kotsopoulos, I.
|
Kucukmetin, A.
|
Mukhopadhyay, A.
| +2
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3
PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia
enthalten in:
Oncotarget
| 2015
von
Herriott, A.
|
Tudhope, S.
|
Junge, G.
| +13
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4
PARP activity in peripheral blood lymphocytes as a predictive biomarker for PARP inhibition in tumor tissues - A population pharmacokinetic/pharmacodynamic analysis of rucaparib
enthalten in:
Clinical pharmacology in drug development
| 2015
von
Wang, D.
|
Li, C.
|
Sun, W.
| +7
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5
Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma
enthalten in:
Current opinion in oncology
| 2014
von
Vormoor, B.
|
Curtin, N.
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6
PARP inhibitors for anticancer therapy
enthalten in:
Biochemical Society transactions
| 2014
von
Curtin, N.
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7
Therapeutic applications of PARP inhibitors : anticancer therapy and beyond
enthalten in:
Molecular aspects of medicine
| 2013
von
Curtin, N.
|
Szabo, C.
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8
Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies
enthalten in:
Haematologica
| 2013
von
Gaymes, T.
|
Mohamedali, A.
|
Patterson, M.
| +8
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9
Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2
enthalten in:
Journal of the National Cancer Institute
| 2011
von
Drew, Y.
|
Mulligan, E.
|
Vong, W.
| +9
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10
Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials
enthalten in:
Cancer chemotherapy and pharmacology
| 2010
von
Zaremba, T.
|
Thomas, H.
|
Cole, M.
| +2
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Thema: Poly(ADP-ribose) Polymerase Inhibitors
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Thema: Poly(ADP-ribose) Polymerases
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Thema
19
EC 2.4.2.30
19
Journal Article
Poly(ADP-ribose) Polymerase Inhibitors
Poly(ADP-ribose) Polymerases
14
Antineoplastic Agents
12
Research Support, Non-U.S. Gov't
9
Enzyme Inhibitors
6
Review
5
7GR28W0FJI
5
Dacarbazine
5
Indoles
5
PARP1 protein, human
5
Poly (ADP-Ribose) Polymerase-1
5
Temozolomide
5
YF1K15M17Y
4
12794-10-4
4
Benzodiazepines
3
1-(4-dimethylaminomethylphenyl)-8,9-dihydro-7H-...
3
7M7YKX2N15
3
8237F3U7EH
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Erscheinungszeitraum
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2020-
10
2010-2019
8
2000-2009
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