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topic_facet:"EC 2.4.2.30"
topic_facet:"Research Support, Non-U.S. Gov't"
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PubPharm (19)
1
Strategies Employed for the Development of PARP Inhibitors
enthalten in:
Methods in molecular biology (Clifton, N.J.)
| 2017
von
Canan, S.
|
Maegley, K.
|
Curtin, N.
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2
PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia
enthalten in:
Oncotarget
| 2015
von
Herriott, A.
|
Tudhope, S.
|
Junge, G.
| +13
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3
Vasoactivity of rucaparib, a PARP-1 inhibitor, is a complex process that involves myosin light chain kinase, P2 receptors, and PARP itself
enthalten in:
PloS one
| 2015
von
McCrudden, C.
|
O'Rourke, M.
|
Cherry, K.
| +14
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4
Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma
enthalten in:
Current opinion in oncology
| 2014
von
Vormoor, B.
|
Curtin, N.
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5
Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies
enthalten in:
Haematologica
| 2013
von
Gaymes, T.
|
Mohamedali, A.
|
Patterson, M.
| +8
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6
Visualization of a DNA-PK/PARP1 complex
enthalten in:
Nucleic acids research
| 2012
von
Spagnolo, L.
|
Barbeau, J.
|
Curtin, N.
| +2
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7
Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers
enthalten in:
The Biochemical journal
| 2011
von
Zaremba, T.
|
Thomas, H.
|
Cole, M.
| +3
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8
Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2
enthalten in:
Journal of the National Cancer Institute
| 2011
von
Drew, Y.
|
Mulligan, E.
|
Vong, W.
| +9
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9
Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials
enthalten in:
Cancer chemotherapy and pharmacology
| 2010
von
Zaremba, T.
|
Thomas, H.
|
Cole, M.
| +2
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10
Poly(ADP-Ribose) polymerase-1 and DNA-dependent protein kinase have equivalent roles in double strand break repair following ionizing radiation
enthalten in:
International journal of radiation oncology, biology, physics
| 2009
von
Mitchell, J.
|
Smith, G.
|
Curtin, N.
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1
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Thema: EC 2.4.2.30
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Thema: Research Support, Non-U.S. Gov't
Medienart
19
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Thema
EC 2.4.2.30
19
Journal Article
Research Support, Non-U.S. Gov't
17
Poly(ADP-ribose) Polymerases
14
Poly(ADP-ribose) Polymerase Inhibitors
10
Enzyme Inhibitors
9
Antineoplastic Agents
9
Poly (ADP-Ribose) Polymerase-1
7
7GR28W0FJI
7
Dacarbazine
7
PARP1 protein, human
7
Temozolomide
7
YF1K15M17Y
5
Indoles
4
12794-10-4
4
8237F3U7EH
4
Benzodiazepines
4
rucaparib
3
1-(4-dimethylaminomethylphenyl)-8,9-dihydro-7H-...
3
7M7YKX2N15
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Erscheinungszeitraum
9
2010-2019
10
2000-2009
Erscheinungsjahr(e)
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Sprache
19
Englisch
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