Zebrafish as a New Model to Study the Crosstalk between Tumor and Host Metabolism
Copyright © 2021 Elsevier Inc. All rights reserved..
The mechanism of metabolic crosstalk between different tissues in the host remains poorly understood but is likely to play important roles in tumor growth and cachexia. A recent study from Naser, Jackstadt, et al. utilizes isotope tracing in a zebrafish melanoma model and finds that tumors secrete alanine into circulation, which is taken up by the liver and used for gluconeogenesis.
| Errataetall: |
CommentOn: Cell Metab. 2021 Jul 6;33(7):1493-1504.e5. - PMID 33989520 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:7 |
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| Enthalten in: |
Trends in cancer - 7(2021), 8 vom: 06. Aug., Seite 661-663 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Montal, Emily [VerfasserIn] |
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Date Completed 05.08.2021 Date Revised 04.01.2022 published: Print-Electronic CommentOn: Cell Metab. 2021 Jul 6;33(7):1493-1504.e5. - PMID 33989520 Citation Status MEDLINE |
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| doi: |
10.1016/j.trecan.2021.06.006 |
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NLM327899921 |
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| 520 | |a The mechanism of metabolic crosstalk between different tissues in the host remains poorly understood but is likely to play important roles in tumor growth and cachexia. A recent study from Naser, Jackstadt, et al. utilizes isotope tracing in a zebrafish melanoma model and finds that tumors secrete alanine into circulation, which is taken up by the liver and used for gluconeogenesis | ||
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