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PubPharm (9.095)
111
Use of selective substrates and inhibitors to rapidly characterise batches of cryopreserved primary human hepatocytes for assessment of active uptake liability in drug discovery and development
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Golding, M.
|
Light, O.
|
Williamson, B.
| +1
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112
Application of physiologically based pharmacokinetic models for therapeutic proteins and other novel modalities
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Rose, R.
|
Sepp, A.
|
Stader, F.
| +3
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113
Non-specific binding of compounds in in vitro metabolism assays : a comparison of microsomal and hepatocyte binding in different species and an assessment of the accuracy of prediction models
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Gardner, I.
|
Xu, M.
|
Han, C.
| +11
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114
One small step in time, one giant leap for DMPK kind - a CRO perspective of the evolving core discipline of drug development
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Kendrick, J.
|
Webber, C.
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115
An HPLC-UV validated bioanalytical method for measurement of in vitro phase 1 kinetics of α-synuclein binding bifunctional compounds
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Aigbogun, O.
|
Nwabufo, C.
|
Owens, M.
| +4
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116
The 50th anniversary of the DMDG
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Taylor, S.
|
Henshall, J.
|
Beaumont, K.
| +4
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117
A translational strategy employing physiologically based modelling to predict the pharmacological active dose of RO7119929, an oral prodrug of a targeted cancer immunotherapy TLR7 agonist
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Rynn, C.
|
Umehara, K.
|
Jiang, T.
| +2
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118
A discovery biotransformation strategy : combining in silico tools with high-resolution mass spectrometry and software-assisted data analysis for high-throughput metabolism
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Weston, D.
|
Dave, M.
|
Colizza, K.
| +6
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119
Time matters - in vitro cellular disposition kinetics help rationalizing cellular potency disconnects
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Poller, B.
|
Werner, S.
|
Domange, N.
| +6
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120
A commentary on the use of pharmacoenhancers in the pharmaceutical industry and the implication for DMPK drug discovery strategies
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Martins, V.
|
Fazal, L.
|
Oganesian, A.
| +4
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