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PubPharm (11)
1
Safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of WBP216, a novel IL-6 monoclonal antibody, in patients with rheumatoid arthritis : A phase Ia randomized placebo-controlled study
enthalten in:
Frontiers in immunology
| 2022
von
Leng, X.
|
Tang, X.
|
Hu, P.
| +6
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2
Modeling and Simulation to Support Phase Ib/IIa Dose Selection for WBP216, A Long Half-Life Fully Human Monoclonal Antibody Against Interleukin-6
enthalten in:
Frontiers in pharmacology
| 2021
von
Tang, X.
|
Zeng, X.
|
Guan, X.
| +2
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3
Predicted contributions of cytochrome P450s to drug metabolism in human liver microsomes using relative activity factor were dependent on probes
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2019
von
Wang, S.
|
Tang, X.
|
Yang, T.
| +4
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4
Predicted contributions of cytochrome P450s to drug metabolism in human liver microsomes using relative activity factor were dependent on probes
enthalten in:
Xenobiotica
| 2019
von
Wang, S.
|
Tang, X.
|
Yang, T.
| +4
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5
In vitro metabolism of l-corydalmine, a potent analgesic drug, in human, cynomolgus monkey, beagle dog, rat and mouse liver microsomes
enthalten in:
Journal of pharmaceutical and biomedical analysis
| 2016
von
Tang, X.
|
Di, X.
|
Zhong, Z.
| +9
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6
Interspecies differences in metabolism of deoxypodophyllotoxin in hepatic microsomes from human, monkey, rat, mouse and dog
enthalten in:
Drug metabolism and pharmacokinetics
| 2016
von
Xie, Q.
|
Chen, Y.
|
Liu, F.
| +8
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7
Sensitive determination of glucose in Dulbecco's modified Eagle medium by high-performance liquid chromatography with 1-phenyl-3-methyl-5-pyrazolone derivatization : application to gluconeogenesis studies
enthalten in:
Biomedical chromatography : BMC
| 2016
von
Ling, Z.
|
Xu, P.
|
Zhong, Z.
| +6
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8
Involvement of pregnane X receptor in the impaired glucose utilization induced by atorvastatin in hepatocytes
enthalten in:
Biochemical pharmacology
| 2016
von
Ling, Z.
|
Shu, N.
|
Xu, P.
| +11
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9
Involvement of pregnane X receptor in the impaired glucose utilization induced by atorvastatin in hepatocytes
enthalten in:
Biochemical pharmacology
| 2016
von
Ling, Z.
|
Shu, N.
|
Xu, P.
| +11
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10
In vitro metabolism of l-corydalmine, a potent analgesic drug, in human, cynomolgus monkey, beagle dog, rat and mouse liver microsomes
enthalten in:
Journal of pharmaceutical and biomedical analysis
| 2016
von
Tang, X.
|
Di, X.
|
Zhong, Z.
| +9
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Xenobiotica
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Xenobiotica; the fate of foreign compounds in b...
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Thema
8
Journal Article
4
Research Support, Non-U.S. Gov't
3
9035-51-2
3
Cytochrome P-450 Enzyme System
2
A0JWA85V8F
2
Atorvastatin
2
CYP450 contribution
2
Cytochrome P450s
2
Glucose
2
Hepatic microsomes
2
IY9XDZ35W2
2
Metabolism
2
cytochrome P450
2
intrinsic clearance
2
probe-dependence
2
relative activity factor
2
rheumatoid arthritis
1
0I8Y3P32UF
1
1-phenyl-3-methyl-5-pyrazolone
1
144O8QL0L1
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2020-
9
2010-2019
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