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topic_facet:"BRCA1 Protein"
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PubPharm (53)
1
The Clinical Implications of Reversions in Patients with Advanced Pancreatic Cancer and Pathogenic Variants in BRCA1, BRCA2, or PALB2 after Progression on Rucaparib
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2023
von
Brown, T.
|
Yablonovitch, A.
|
Till, J.
| +11
CommentIn: Clin Cancer Res. 2023 Dec 15;29(24):5005-5007. - PMID 37787975
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2
Real-World Efficacy and Safety of PARP Inhibitors in Recurrent Ovarian Cancer Patients With Somatic BRCA and Other Homologous Recombination Gene Mutations
enthalten in:
The Annals of pharmacotherapy
| 2023
von
Pan, Y.
|
Hood, A.
|
Ahmad, H.
| +1
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3
Rucaparib improves PFS in patients with BRCA1/2-altered mCRPC
enthalten in:
Nature reviews. Urology
| 2023
von
Stone, L.
CommentOn: N Engl J Med. 2023 Feb 23;388(8):719-732. - PMID 36795891
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4
The effect of PARP inhibitors in homologous recombination proficient ovarian cancer : meta-analysis
enthalten in:
Journal of chemotherapy (Florence, Italy)
| 2023
von
Skelin, M.
|
Šarčević, D.
|
Lešin Gaćina, D.
| +3
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5
Rucaparib for recurrent ovarian cancer with BRCA1 and BRCA2 mutations
enthalten in:
The Lancet. Oncology
| 2022
von
Ganguly, S.
|
Gogia, A.
CommentOn: Lancet Oncol. 2022 Apr;23(4):465-478. - PMID 35298906
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6
Rucaparib for recurrent ovarian cancer with BRCA1 and BRCA2 mutations - Authors' reply
enthalten in:
The Lancet. Oncology
| 2022
von
Kristeleit, R.
|
Oza, A.
CommentOn: Lancet Oncol. 2022 Apr;23(4):465-478. - PMID 35298906
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7
Rucaparib for BRCA1/2-mutated pretreated ovarian cancer : reflections from the ARIEL4 trial
enthalten in:
The Lancet. Oncology
| 2022
von
O'Donnell, D.
CommentOn: Lancet Oncol. 2022 Apr;23(4):465-478. - PMID 35298906
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8
Rucaparib versus standard-of-care chemotherapy in patients with relapsed ovarian cancer and a deleterious BRCA1 or BRCA2 mutation (ARIEL4) : an international, open-label, randomised, phase 3 trial
enthalten in:
The Lancet. Oncology
| 2022
von
Kristeleit, R.
|
Lisyanskaya, A.
|
Fedenko, A.
| +22
CommentIn: Lancet Oncol. 2022 Apr;23(4):440-441. - PMID 35298905
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9
Structure-based design, synthesis, and evaluation of inhibitors with high selectivity for PARP-1 over PARP-2
enthalten in:
European journal of medicinal chemistry
| 2022
von
Yu, J.
|
Luo, L.
|
Hu, T.
| +6
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10
Characterization of patients with long-term responses to rucaparib treatment in recurrent ovarian cancer
enthalten in:
Gynecologic oncology
| 2021
von
Swisher, E.
|
Kristeleit, R.
|
Oza, A.
| +19
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Thema: BRCA1 Protein
Medienart
53
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5
The Lancet. Oncology
4
Clinical cancer research : an official journal ...
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Gynecologic oncology
3
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3
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2
Cancer discovery
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Thema
BRCA1 Protein
49
Journal Article
49
rucaparib
45
8237F3U7EH
45
Indoles
45
Poly(ADP-ribose) Polymerase Inhibitors
41
BRCA1 protein, human
40
BRCA2 Protein
32
BRCA2 protein, human
24
Research Support, Non-U.S. Gov't
16
olaparib
12
EC 2.4.2.30
12
Phthalazines
12
Piperazines
12
Review
12
WOH1JD9AR8
11
Antineoplastic Agents
11
Clinical Trial, Phase II
11
niraparib
10
Poly(ADP-ribose) Polymerases
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Erscheinungszeitraum
27
2020-
26
2010-2019
Erscheinungsjahr(e)
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Sprache
52
Englisch
1
Japanisch
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