Suchergebnisse - "multitarget ligands"

PubPharm (47)

11

Evaluation of γ-carboline-phenothiazine conjugates as simultaneous NMDA receptor blockers and cholinesterase inhibitors

enthalten in: Bioorganic & medicinal chemistry | 2021

von Schwarthoff, S. | Tischer, N. | Sager, H. | +7

12

LP1 and LP2 : Dual-Target MOPr/DOPr Ligands as Drug Candidates for Persistent Pain Relief

enthalten in: Molecules (Basel, Switzerland) | 2021

von Pasquinucci, L. | Parenti, C. | Georgoussi, Z. | +3

13

Antinociceptive Efficacy of the µ-Opioid/Nociceptin Peptide-Based Hybrid KGNOP1 in Inflammatory Pain without Rewarding Effects in Mice : An Experimental Assessment and Molecular Docking

enthalten in: Molecules (Basel, Switzerland) | 2021

von Dumitrascuta, M. | Bermudez, M. | Trovato, O. | +4

14

Design, Synthesis, and In Silico Multitarget Pharmacological Simulations of Acid Bioisosteres with a Validated In Vivo Antihyperglycemic Effect

enthalten in: Molecules (Basel, Switzerland) | 2021

von Domínguez-Mendoza, E. | Galván-Ciprés, Y. | Martínez-Miranda, J. | +6

15

Antinociceptive Efficacy of the µ-Opioid/Nociceptin Peptide-Based Hybrid KGNOP1 in Inflammatory Pain without Rewarding Effects in Mice: An Experimental Assessment and Molecular Docking

in: Molecules | 2021

von Maria Dumitrascuta | Marcel Bermudez | Olga Trovato | +4

16

LP1 and LP2: Dual-Target MOPr/DOPr Ligands as Drug Candidates for Persistent Pain Relief

in: Molecules | 2021

von Lorella Pasquinucci | Carmela Parenti | Zafiroula Georgoussi | +3

17

Solid Lipid Nanoparticles as Carriers for the Synthetic Opioid LP2: Characterization and In Vitro Release

in: Applied Sciences | 2021

von Angelo Spadaro | Lorella Pasquinucci | Miriam Lorenti | +5

18

Design, Synthesis, and In Silico Multitarget Pharmacological Simulations of Acid Bioisosteres with a Validated In Vivo Antihyperglycemic Effect

in: Molecules | 2021

von Elix Alberto Domínguez-Mendoza | Yelzyn Galván-Ciprés | Josué Martínez-Miranda | +6

19

In Vivo, In Vitro and In Silico Studies of the Hybrid Compound AA3266, an Opioid Agonist/NK1R Antagonist with Selective Cytotoxicity

enthalten in: International journal of molecular sciences | 2020

von Matalińska, J. | Lipiński, P. | Kosson, P. | +2

20

Discovery of biphenyl pyrazole scaffold for neurodegenerative diseases : A novel class of acetylcholinesterase-centered multitargeted ligands

enthalten in: Bioorganic & medicinal chemistry letters | 2020

von Gabr, M. | Murugan, N.