Suchergebnisse - "de Koning, Harry P"

PubPharm (23)

1

Differences in Transporters Rather than Drug Targets Are the Principal Determinants of the Different Innate Sensitivities of Trypanosoma congolense and Trypanozoon Subgenus Trypanosomes to Diamidines and Melaminophenyl Arsenicals

enthalten in: International journal of molecular sciences | 2022

von Ungogo, M. | Campagnaro, G. | Alghamdi, A. | +2

2

Direct, Late-Stage Mono-N-arylation of Pentamidine : Method Development, Mechanistic Insight, and Expedient Access to Novel Antiparastitics against Diamidine-Resistant Parasites

enthalten in: ChemMedChem | 2021

von Robertson, J. | Ungogo, M. | Aldfer, M. | +7

3

Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei

enthalten in: eLife | 2020

von Alghamdi, A. | Munday, J. | Campagnaro, G. | +32

4

Novel Minor Groove Binders Cure Animal African Trypanosomiasis in an in Vivo Mouse Model

enthalten in: Journal of medicinal chemistry | 2019

von Giordani, F. | Khalaf, A. | Gillingwater, K. | +5

ErratumIn: J Med Chem. 2021 Dec 23;64(24):18236. - PMID 34854304

5

Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense

enthalten in: Cellular and molecular life sciences : CMLS | 2016

von Graf, F. | Ludin, P. | Arquint, C. | +11

6

Chimerization at the AQP2-AQP3 locus is the genetic basis of melarsoprol-pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates

enthalten in: International journal for parasitology. Drugs and drug resistance | 2015

von Graf, F. | Baker, N. | Munday, J. | +3

7

Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis

enthalten in: PLoS pathogens | 2015

von Unciti-Broceta, J. | Arias, J. | Maceira, J. | +7

8

Functional analysis of drug resistance-associated mutations in the Trypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein

enthalten in: Molecular microbiology | 2015

von Munday, J. | Tagoe, D. | Eze, A. | +8

9

Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs

enthalten in: The Journal of antimicrobial chemotherapy | 2014

von Munday, J. | Eze, A. | Baker, N. | +17

10

Drug resistance in African trypanosomiasis : the melarsoprol and pentamidine story

enthalten in: Trends in parasitology | 2013

von Baker, N. | de Koning, H. | Mäser, P. | +1