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PubPharm (122)
1
Novel bioactive 2-phenyl-4-aminopyrimidine derivatives as EGFRDel19/T790M/C797S inhibitors for the treatment of non-small cell lung cancer
enthalten in:
Archiv der Pharmazie
| 2024
von
Xu, S.
|
Zhou, Z.
|
He, J.
| +6
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2
Research progress on small molecule inhibitors targeting KRAS G12C with acrylamide structure and the strategies for solving KRAS inhibitor resistance
enthalten in:
Bioorganic & medicinal chemistry
| 2024
von
Jiang, Z.
|
Li, Y.
|
Zhou, X.
| +3
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3
Insights into the Overcoming EGFRDel19/T790M/C797S Mutation : A Perspective on the 2-aryl-4-aminothienopyrimidine Backbone
enthalten in:
ChemMedChem
| 2024
von
Zhang, X.
|
He, J.
|
Xu, S.
| +5
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4
Novel quinazoline-based dual EGFR/c-Met inhibitors overcoming drug resistance for the treatment of NSCLC : Design, synthesis and anti-tumor activity
enthalten in:
Bioorganic chemistry
| 2024
von
Zhang, H.
|
Gan, W.
|
Fan, D.
| +4
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5
T6496 targeting EGFR mediated by T790M or C797S mutant : machine learning, virtual screening and bioactivity evaluation study
enthalten in:
Journal of biomolecular structure & dynamics
| 2024
von
Wang, L.
|
Fan, D.
|
Ruan, W.
| +4
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6
T5S1607 identified as a antibacterial FtsZ inhibitor:Virtual screening combined with bioactivity evaluation for the drug discovery
enthalten in:
Computational biology and chemistry
| 2024
von
Xie, Z.
|
Ruan, W.
|
Guo, J.
| +9
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7
Novel bioactive 2‐phenyl‐4‐aminopyrimidine derivatives as EGFR Del19/T790M/C797S inhibitors for the treatment of non‐small cell lung cancer
enthalten in:
Archiv der Pharmazie
| 2024
von
Xu, S.
|
Zhou, Z.
|
He, J.
| +6
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8
Non-small cell lung cancer cells with uncommon EGFR exon 19delins variants respond poorly to third-generation EGFR inhibitors
enthalten in:
Translational oncology
| 2024
von
Lu, Z.
|
Yi, Y.
|
Wang, L.
| +9
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9
Design, synthesis, and biological evaluation of 4-(2-fluorophenoxy)-7-methoxyquinazoline derivatives as dual EGFR/c-Met inhibitors for the treatment of NSCLC
enthalten in:
European journal of medicinal chemistry
| 2024
von
Tang, S.
|
Sun, C.
|
He, X.
| +7
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10
Discovery of novel potent PI3K/mTOR dual-target inhibitors based on scaffold hopping : Design, synthesis, and antiproliferative activity
enthalten in:
Archiv der Pharmazie
| 2023
von
Yang, Y.
|
Sun, X.
|
Luo, L.
| +9
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47
Antineoplastic Agents
35
EC 2.7.10.1
35
Protein Kinase Inhibitors
27
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22
Pyrimidines
19
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16
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14
Proto-Oncogene Proteins c-met
12
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11
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9
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EC 2.7.11.1
9
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9
TOR Serine-Threonine Kinases
8
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