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topic_facet:"Pyrimidines"
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PubPharm (8)
1
Development of Furanopyrimidine-Based Orally Active Third-Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung Cancer
enthalten in:
Journal of medicinal chemistry
| 2023
von
Li, M.
|
Coumar, M.
|
Lin, S.
| +16
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2
Discovery and Synthesis of a Pyrimidine-Based Aurora Kinase Inhibitor to Reduce Levels of MYC Oncoproteins
enthalten in:
Journal of medicinal chemistry
| 2021
von
Chi, Y.
|
Yeh, T.
|
Ke, Y.
| +17
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3
Identification of a Multitargeted Tyrosine Kinase Inhibitor for the Treatment of Gastrointestinal Stromal Tumors and Acute Myeloid Leukemia
enthalten in:
Journal of medicinal chemistry
| 2019
von
Lin, W.
|
Wu, S.
|
Yeh, T.
| +25
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4
Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer
enthalten in:
Journal of medicinal chemistry
| 2019
von
Lin, S.
|
Chang Hsu, Y.
|
Peng, Y.
| +17
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5
Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents
enthalten in:
Future medicinal chemistry
| 2019
von
Liu, Y.
|
Chen, C.
|
Yeh, T.
| +1
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6
Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants
enthalten in:
Journal of medicinal chemistry
| 2019
von
Wu, T.
|
Lin, W.
|
Tsai, H.
| +18
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7
BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells
enthalten in:
PloS one
| 2011
von
Cheung, C.
|
Lin, W.
|
Hsu, J.
| +11
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8
Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors : the role of side chain chirality and Michael acceptor group for maximal potency
enthalten in:
Journal of medicinal chemistry
| 2010
von
Wu, C.
|
Coumar, M.
|
Chu, C.
| +20
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1
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Thema: Pyrimidines
Medienart
8
Aufsätze
8
E-Artikel
8
E-Ressourcen
Zeitschriftentitel
6
Journal of medicinal chemistry
1
Future medicinal chemistry
1
PloS one
Thema
8
Journal Article
Pyrimidines
8
Research Support, Non-U.S. Gov't
6
Antineoplastic Agents
6
Protein Kinase Inhibitors
5
EC 2.7.10.1
3
ErbB Receptors
2
Aurora Kinase A
2
Aurora Kinase B
2
EC 2.7.11.1
2
EGFR protein, human
2
Proto-Oncogene Proteins c-kit
1
1-(4-((2-hydroxy-1-phenylethyl)amino)-5,6,7,8-t...
1
4-(dimethylamino)-1-(4-(2-hydroxy-1-phenylethyl...
1
8A1O1M485B
1
8W8T17847W
1
ATP Binding Cassette Transporter, Subfamily B, ...
1
AURKB protein, human
1
Aurka protein, mouse
1
Aurka protein, rat
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Erscheinungszeitraum
2
2020-
6
2010-2019
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Sprache
8
Englisch
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