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PubPharm (86)
31
Development of Novel, CNS Penetrant Positive Allosteric Modulators for the Metabotropic Glutamate Receptor Subtype 1 (mGlu1), Based on an N-(3-Chloro-4-(1,3-dioxoisoindolin-2-yl)phenyl)-3-methylfuran-2-carboxamide Scaffold, That Potentiate Wild Type and Mutant mGlu1 Receptors Found in Schizophrenics
enthalten in:
Journal of medicinal chemistry
| 2015
von
Garcia-Barrantes, P.
|
Cho, H.
|
Niswender, C.
| +7
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32
Activation of Metabotropic Glutamate Receptor 7 Is Required for Induction of Long-Term Potentiation at SC-CA1 Synapses in the Hippocampus
enthalten in:
The journal of neuroscience
| 2015
von
Klar, R.
|
Walker, A.
|
Ghose, D.
| +7
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33
Allosteric activation of M4muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice
enthalten in:
Proceedings of the National Academy of Sciences of the United States of America
| 2015
von
Conn, P.
|
Wood, M.
|
Bradley, E.
| +14
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34
Allosteric activation of [M.sub.4] muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice
enthalten in:
Proceedings of the National Academy of Sciences of the United States of America
| 2015
von
Conn, P.
|
Wood, M.
|
Bradley, E.
| +14
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35
Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7
enthalten in:
ACS chemical neuroscience
| 2014
von
Field, J.
|
Klar, R.
|
Mattmann, M.
| +19
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36
M4 mAChR-mediated modulation of glutamatergic transmission at corticostriatal synapses
enthalten in:
ACS chemical neuroscience
| 2014
von
Pancani, T.
|
Bolarinwa, C.
|
Smith, Y.
| +3
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37
M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location
enthalten in:
The Journal of neuroscience : the official journal of the Society for Neuroscience
| 2014
von
Foster, D.
|
Gentry, P.
|
Lizardi-Ortiz, J.
| +7
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38
M5 Receptor Activation Produces Opposing Physiological Outcomes in Dopamine Neurons Depending on the Receptor's Location
enthalten in:
The journal of neuroscience
| 2014
von
Foster, D.
|
Gentry, P.
|
Lizardi-Ortiz, J.
| +7
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39
Influence of M1 muscarinic acetylcholine receptor activation on arousal and cognitive performance using electroencephalography and novel touchscreen cognition assessment (845.5)
enthalten in:
The FASEB Journal
| 2014
von
Gould, R.
|
Nedelcovych, M.
|
Dencker, D.
| +8
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40
Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs) : discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254)
enthalten in:
Journal of medicinal chemistry
| 2013
von
Turlington, M.
|
Noetzel, M.
|
Chun, A.
| +16
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Thema
51
Journal Article
36
Research Support, N.I.H., Extramural
28
Research Support, Non-U.S. Gov't
16
Receptors, Metabotropic Glutamate
9
Receptor, Metabotropic Glutamate 5
9
Receptor, Muscarinic M1
6
Calcium
6
SY7Q814VUP
5
3KX376GY7L
5
Antipsychotic Agents
5
Cholinergic Agents
5
Excitatory Amino Acid Antagonists
5
Glutamic Acid
5
Picolinic Acids
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Receptor, Muscarinic M4
5
Receptors, N-Methyl-D-Aspartate
5
metabotropic glutamate receptor 3
4
Muscarinic Agonists
4
metabotropic glutamate receptor 2
3
Acetylcholine
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Erscheinungszeitraum
82
2000-
1
1900-1999
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Englisch
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