Suchergebnisse - "Wood, Michael W"

PubPharm (15)

1

Islet allografts expressing a PD-L1 and IDO fusion protein evade immune rejection and reverse preexisting diabetes in immunocompetent mice without systemic immunosuppression

enthalten in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons | 2022

von Paul, P. | Das, R. | Drow, T. | +7

ErratumIn: Am J Transplant. 2023 May;23(5):693. - PMID 36907701

2

An immunohistochemical prostate cell identification key indicates that aging shifts procollagen 1A1 production from myofibroblasts to fibroblasts in dogs prone to prostate-related urinary dysfunction

enthalten in: PloS one | 2020

von Ruetten, H. | Cole, C. | Wehber, M. | +9

3

SAR inspired by aldehyde oxidase (AO) metabolism : Discovery of novel, CNS penetrant tricyclic M4 PAMs

enthalten in: Bioorganic & medicinal chemistry letters | 2019

von Chopko, T. | Han, C. | Gregro, A. | +24

4

VU6005806/AZN-00016130, an advanced M4 positive allosteric modulator (PAM) profiled as a potential preclinical development candidate

enthalten in: Bioorganic & medicinal chemistry letters | 2019

von Engers, D. | Melancon, B. | Gregro, A. | +18

ErratumIn: Bioorg Med Chem. 2020 Dec 15;28(24):115825. - PMID 33218899

5

Prostatic collagen architecture in neutered and intact canines

enthalten in: The Prostate | 2018

von Ruetten, H. | Wegner, K. | Romero, M. | +5

6

Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway

enthalten in: Journal of lipid research | 2018

von Fan, J. | Zhao, R. | Parro, C. | +15

ErratumIn: J Lipid Res. 2022 May;63(5):100214. - PMID 35500417

7

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

enthalten in: Nature | 2017

von Shi, Y. | Yamada, K. | Liddelow, S. | +31

CommentIn: Nat Rev Neurol. 2017 Dec;13(12):706-707. - PMID 28984314

8

Challenges in the development of an M4 PAM preclinical candidate : The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides

enthalten in: Bioorganic & medicinal chemistry letters | 2017

von Tarr, J. | Wood, M. | Noetzel, M. | +15

9

Challenges in the development of an M4 PAM in vivo tool compound : The discovery of VU0467154 and unexpected DMPK profiles of close analogs

enthalten in: Bioorganic & medicinal chemistry letters | 2017

von Wood, M. | Noetzel, M. | Poslusney, M. | +17

10

Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core : Challenges in disposition

enthalten in: Bioorganic & medicinal chemistry letters | 2016

von Wood, M. | Noetzel, M. | Tarr, J. | +15