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PubPharm (126)
1
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets
enthalten in:
Nature metabolism
| 2023
von
El, K.
|
Douros, J.
|
Willard, F.
| +14
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2
Mutual Cooperativity of Three Allosteric Sites on the Dopamine D1 Receptor
enthalten in:
Molecular pharmacology
| 2023
von
Wang, X.
|
Hembre, E.
|
Goldsmith, P.
| +4
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3
LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss : From discovery to clinical proof of concept
enthalten in:
Cell metabolism
| 2022
von
Coskun, T.
|
Urva, S.
|
Roell, W.
| +17
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4
Structural determinants of dual incretin receptor agonism by tirzepatide
enthalten in:
Proceedings of the National Academy of Sciences of the United States of America
| 2022
von
Sun, B.
|
Willard, F.
|
Feng, D.
| +20
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5
Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide-1 Receptor
enthalten in:
Journal of medicinal chemistry
| 2021
von
Willard, F.
|
Wainscott, D.
|
Showalter, A.
| +16
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6
Nuisance compounds in cellular assays
enthalten in:
Cell chemical biology
| 2021
von
Dahlin, J.
|
Auld, D.
|
Rothenaigner, I.
| +13
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7
A High-Throughput Assay for the Pancreatic Islet Beta-Cell Potassium Channel : Use in the Pharmacological Characterization of Insulin Secretagogues Identified from Phenotypic Screening
enthalten in:
Assay and drug development technologies
| 2021
von
Song, L.
|
Barrett, D.
|
Cox, K.
| +4
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8
A synthetic method to assay adhesion-family G-protein coupled receptors. Determination of the G-protein coupling profile of ADGRG6(GPR126)
enthalten in:
Biochemical and biophysical research communications
| 2021
von
Lizano, E.
|
Hayes, J.
|
Willard, F.
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9
Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist
enthalten in:
Proceedings of the National Academy of Sciences of the United States of America
| 2020
von
Kawai, T.
|
Sun, B.
|
Yoshino, H.
| +13
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10
Structural insights into probe-dependent positive allosterism of the GLP-1 receptor
enthalten in:
Nature chemical biology
| 2020
von
Bueno, A.
|
Sun, B.
|
Willard, F.
| +16
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31
Research Support, N.I.H., Extramural
22
RGS Proteins
21
EC 3.6.5.1
21
GTP-Binding Protein alpha Subunits
18
Research Support, U.S. Gov't, P.H.S.
17
Glucagon-Like Peptide-1 Receptor
12
Review
11
Recombinant Fusion Proteins
10
Insulin
10
Receptors, G-Protein-Coupled
9
Cyclic AMP
9
E0399OZS9N
9
GTP-Binding Protein alpha Subunits, Gi-Go
9
Heterotrimeric GTP-Binding Proteins
9
Peptides
8
GLP1R protein, human
8
Receptors, Glucagon
7
89750-14-1
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