Suchergebnisse - "Wickremsinhe, Enaksha R"

PubPharm (14)

1

Phase I Study of CHK1 Inhibitor LY2603618 in Combination with Gemcitabine in Patients with Solid Tumors

enthalten in: Oncology | 2016

von Calvo, E. | Braiteh, F. | Von Hoff, D. | +11

2

Phase I dose escalation and pharmacokinetic evaluation of two different schedules of LY2334737, an oral gemcitabine prodrug, in patients with advanced solid tumors

enthalten in: Investigational new drugs | 2015

von Faivre, S. | Olszanski, A. | Weigang-Köhler, K. | +10

3

Automated high‐capacity on‐line extraction and bioanalysis of dried blood spot samples using liquid chromatography/high‐resolution accurate mass spectrometry

enthalten in: Rapid communications in mass spectrometry | 2014

von Oliveira, R. | Henion, J. | Wickremsinhe, E.

4

Disposition and metabolism of LY2603618, a Chk-1 inhibitor following intravenous administration in patients with advanced and/or metastatic solid tumors

enthalten in: Xenobiotica | 2014

von Wickremsinhe, E. | Hynes, S. | Palmieri, M. | +6

5

Phase 1 dose escalation and pharmacokinetic evaluation of oral gemcitabine prodrug (LY2334737) in combination with docetaxel in patients with advanced solid tumors

enthalten in: Cancer chemotherapy and pharmacology | 2014

von Salazar, R. | Morales, S. | Gil-Martín, M. | +7

6

High sensitive assay employing column switching chromatography to enable simultaneous quantification of an amide prodrug of gemcitabine (LY2334737), gemcitabine, and its metabolite dFdU in human plasma by LC–MS/MS

enthalten in: Journal of chromatography / B | 2013

von Wickremsinhe, E. | Lee, L. | Schmalz, C. | +2

7

Preclinical bridging studies: Understanding dried blood spot and plasma exposure profiles

enthalten in: Bioanalysis | 2013

von Wickremsinhe, E. | Huang, N. | Abdul, B. | +3

8

Validation of 96‐well equilibrium dialysis with non‐radiolabeled drug for definitive measurement of protein binding and application to clinical development of highly‐bound drugs

enthalten in: Journal of pharmaceutical sciences | 2011

von Zamek‐Gliszczynski, M. | Ruterbories, K. | Ajamie, R. | +7

9

Quantification of Gemcitabine Incorporation into Human DNA by LC/MS/MS as a Surrogate Measure for Target Engagement

enthalten in: Analytical chemistry | 2010

von Wickremsinhe, E. | Lutzke, B. | Jones, B. | +5

10

Stereoselective metabolism of prasugrel in humans using a novel chiral liquid chromatography-tandem mass spectrometry method

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2007

von Wickremsinhe, E. | Tian, Y. | Ruterbories, K. | +4