Suchergebnisse - "Venkatakrishnan, Karthik"

PubPharm (18)

1

Phase 1 Study to Evaluate the Effect of the Investigational Anticancer Agent Sapanisertib on the QTc Interval in Patients With Advanced Solid Tumors

enthalten in: Clinical pharmacology in drug development | 2020

von Patel, C. | Goel, S. | Patel, M. | +5

2

Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2020

von Pusalkar, S. | Zhou, X. | Li, Y. | +8

3

Pharmacokinetics of the Investigational Aurora A Kinase Inhibitor Alisertib in Adult Patients With Advanced Solid Tumors or Relapsed/Refractory Lymphoma With Varying Degrees of Hepatic Dysfunction

enthalten in: Journal of clinical pharmacology | 2019

von Zhou, X. | Lockhart, A. | Fu, S. | +6

4

Mass balance, routes of excretion, and pharmacokinetics of investigational oral [14C]-alisertib (MLN8237), an Aurora A kinase inhibitor in patients with advanced solid tumors

enthalten in: Investigational new drugs | 2019

von Zhou, X. | Pusalkar, S. | Chowdhury, S. | +4

5

Randomized Phase III Study of Alisertib or Investigator's Choice (Selected Single Agent) in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma

enthalten in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology | 2019

von O'Connor, O. | Özcan, M. | Jacobsen, E. | +27

6

Phase I Study of the Investigational Aurora A Kinase Inhibitor Alisertib plus Rituximab or Rituximab/Vincristine in Relapsed/Refractory Aggressive B-cell Lymphoma

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2018

von Kelly, K. | Friedberg, J. | Park, S. | +22

7

Effects of rifampin, itraconazole and esomeprazole on the pharmacokinetics of alisertib, an investigational aurora a kinase inhibitor in patients with advanced malignancies

enthalten in: Investigational new drugs | 2018

von Zhou, X. | Pant, S. | Nemunaitis, J. | +10

8

Effect of alisertib, an investigational aurora a kinase inhibitor on the QTc interval in patients with advanced malignancies

enthalten in: Investigational new drugs | 2018

von Zhou, X. | Nemunaitis, J. | Pant, S. | +8

9

Global population pharmacokinetics of the investigational Aurora A kinase inhibitor alisertib in cancer patients : rationale for lower dosage in Asia

enthalten in: British journal of clinical pharmacology | 2018

von Zhou, X. | Mould, D. | Takubo, T. | +4

10

Open-label, multicenter, phase 1 study of alisertib (MLN8237), an aurora A kinase inhibitor, with docetaxel in patients with solid tumors

enthalten in: Cancer | 2016

von Graff, J. | Higano, C. | Hahn, N. | +6