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PubPharm (39)
1
Model-Informed Selection of the Recommended Phase III Dose of the Inhibitor of Apoptosis Protein Inhibitor, Xevinapant, in Combination with Cisplatin and Concurrent Radiotherapy in Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck
enthalten in:
Clinical pharmacology and therapeutics
| 2024
von
Vugmeyster, Y.
|
Ravula, A.
|
Rouits, E.
| +7
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2
Response-Based Dosing for Ponatinib : Model-Based Analyses of the Dose-Ranging OPTIC Study
enthalten in:
Clinical pharmacology and therapeutics
| 2023
von
Hanley, M.
|
Diderichsen, P.
|
Rich, B.
| +5
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3
Designing phase I oncology dose escalation using dose-exposure-toxicity models as a complementary approach to model-based dose-toxicity models
enthalten in:
CPT: pharmacometrics & systems pharmacology
| 2022
von
Pantoja, K.
|
Lanke, S.
|
Munafo, A.
| +6
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4
Population Pharmacokinetics of Ponatinib in Healthy Adult Volunteers and Patients With Hematologic Malignancies and Model-Informed Dose Selection for Pediatric Development
enthalten in:
Journal of clinical pharmacology
| 2022
von
Hanley, M.
|
Diderichsen, P.
|
Narasimhan, N.
| +3
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5
Population Pharmacokinetics and Exposure-Safety Relationships of Alisertib in Children and Adolescents With Advanced Malignancies
enthalten in:
Journal of clinical pharmacology
| 2022
von
Zhou, X.
|
Mould, D.
|
Yuan, Y.
| +4
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6
Essential (and Largely Untaught) Skills for Clinical Pharmacology in Oncology Drug Development
enthalten in:
Clinical pharmacology and therapeutics
| 2022
von
Hendriks, B.
|
Venkatakrishnan, K.
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7
Phase 1 Study to Evaluate the Effect of the Investigational Anticancer Agent Sapanisertib on the QTc Interval in Patients With Advanced Solid Tumors
enthalten in:
Clinical pharmacology in drug development
| 2020
von
Patel, C.
|
Goel, S.
|
Patel, M.
| +5
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8
The Changing Face of Oncology Research, Drug Development, and Clinical Practice : Toward Patient-Focused Precision Therapeutics
enthalten in:
Clinical pharmacology and therapeutics
| 2020
von
Venkatakrishnan, K.
|
van der Graaf, P.
|
Holstein, S.
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9
A Translational Physiologically Based Pharmacokinetics/Pharmacodynamics Framework of Target-Mediated Disposition, Target Inhibition and Drug-Drug Interactions of Bortezomib
enthalten in:
The AAPS journal
| 2020
von
Iwasaki, S.
|
Zhu, A.
|
Hanley, M.
| +2
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10
Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2020
von
Pusalkar, S.
|
Zhou, X.
|
Li, Y.
| +8
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Thema: Antineoplastic Agents
Medienart
39
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39
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39
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Zeitschriftentitel
7
Journal of clinical pharmacology
4
Clinical cancer research : an official journal ...
4
Clinical pharmacology and therapeutics
4
Investigational new drugs
3
Cancer chemotherapy and pharmacology
3
Clinical pharmacokinetics
2
British journal of clinical pharmacology
1
CPT: pharmacometrics & systems pharmacology
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The AAPS journal
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Thema
Antineoplastic Agents
38
Journal Article
29
Research Support, Non-U.S. Gov't
17
Clinical Trial, Phase I
14
Pyrimidines
13
Azepines
13
EC 2.7.11.1
13
MLN 8237
12
Protein Kinase Inhibitors
10
Aurora Kinase A
9
Randomized Controlled Trial
8
71050168A2
8
Boron Compounds
8
Glycine
8
Multicenter Study
8
TE7660XO1C
8
ixazomib
7
69G8BD63PP
7
Bortezomib
6
AURKA protein, human
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Erscheinungszeitraum
10
2020-
28
2010-2019
1
2000-2009
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39
Englisch
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