Suchergebnisse - "Ubah, Obinna C"

PubPharm (12)

1

Overview, Generation, and Significance of Variable New Antigen Receptors (VNARs) as a Platform for Drug and Diagnostic Development

enthalten in: Methods in molecular biology (Clifton, N.J.) | 2022

von Pandey, S. | Kovaleva, M. | Barelle, C. | +1

2

Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography

enthalten in: Nature communications | 2021

von Ubah, O. | Lake, E. | Gunaratne, G. | +18

3

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties

enthalten in: Methods in molecular biology (Clifton, N.J.) | 2020

von Steven, J. | Ubah, O. | Buschhaus, M. | +4

4

In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA : An Encouraging Milestone to Further Clinical Drug Development

enthalten in: Journal of immunology research | 2020

von Ubah, O. | Porter, A. | Barelle, C.

5

Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand

enthalten in: Translational vision science & technology | 2019

von Pepple, K. | Wilson, L. | Van Gelder, R. | +5

6

An Anti-hTNF-α Variable New Antigen Receptor Format Demonstrates Superior in vivo Preclinical Efficacy to Humira® in a Transgenic Mouse Autoimmune Polyarthritis Disease Model

enthalten in: Frontiers in immunology | 2019

von Ubah, O. | Steven, J. | Porter, A. | +1

7

Next-generation flexible formats of VNAR domains expand the drug platform's utility and developability

enthalten in: Biochemical Society transactions | 2018

von Ubah, O. | Buschhaus, M. | Ferguson, L. | +4

8

Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development

enthalten in: Frontiers in immunology | 2017

von Ubah, O. | Steven, J. | Kovaleva, M. | +4

9

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

enthalten in: Frontiers in immunology | 2017

von Steven, J. | Müller, M. | Carvalho, M. | +8

10

Phage Display Derived IgNAR V Region Binding Domains for Therapeutic Development

enthalten in: Current pharmaceutical design | 2016

von Ubah, O. | Barelle, C. | Buschhaus, M. | +1