Suchergebnisse - "Tong, Lexian"

PubPharm (11)

1

Design, synthesis, and antitumor activity evaluation of potent fourth-generation EGFR inhibitors for treatment of Osimertinib resistant non-small cell lung cancer (NSCLC)

enthalten in: Bioorganic chemistry | 2024

von Zhang, Y. | Tong, L. | Yan, F. | +3

2

Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors

enthalten in: Bioorganic & medicinal chemistry letters | 2023

von Lian, X. | Gao, Y. | Li, X. | +5

3

Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities

enthalten in: Journal of medicinal chemistry | 2023

von Li, X. | Wang, P. | Wang, C. | +8

4

Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia

enthalten in: Leukemia | 2023

von Jiang, K. | Li, X. | Wang, C. | +14

5

Discovery of new macrophage M2 polarization modulators as multiple sclerosis treatment agents that enable the inflammation microenvironment remodeling

enthalten in: European journal of medicinal chemistry | 2022

von Che, J. | Li, D. | Hong, W. | +8

6

Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells

enthalten in: European journal of medicinal chemistry | 2022

von Qu, B. | Xu, Y. | Lu, Y. | +11

7

Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT

enthalten in: Journal of medicinal chemistry | 2022

von Tong, L. | Wang, P. | Li, X. | +6

8

Recent advances in FLT3 inhibitors for acute myeloid leukemia

enthalten in: Future medicinal chemistry | 2020

von Tong, L. | Li, X. | Hu, Y. | +1

9

Recent advances in FLT3 inhibitors for acute myeloid leukemia

enthalten in: Future medicinal chemistry | 2020

von Tong, L. | Li, X. | Hu, Y. | +1

10

Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino)pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies

enthalten in: European journal of medicinal chemistry | 2019

von Tong, L. | Song, P. | Jiang, K. | +10