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PubPharm (10)
1
Synthesis and Structure-Activity Relationships for the Anti-Mycobacterial Activity of 3-Phenyl-N-(Pyridin-2-ylmethyl)Pyrazolo[1,5-a]Pyrimidin-7-Amines
enthalten in:
Pharmaceuticals (Basel, Switzerland)
| 2022
von
Sutherland, H.
|
Choi, P.
|
Lu, G.
| +6
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2
Synthesis and structure-activity relationships for a new class of tetrahydronaphthalene amide inhibitors of Mycobacterium tuberculosis
enthalten in:
European journal of medicinal chemistry
| 2022
von
Sutherland, H.
|
Lu, G.
|
Tong, A.
| +8
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3
Synthesis and structure-activity relationships for tetrahydroisoquinoline-based inhibitors of Mycobacterium tuberculosis
enthalten in:
Bioorganic & medicinal chemistry
| 2020
von
Lu, G.
|
Tong, A.
|
Conole, D.
| +8
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4
Synthetic Studies to Help Elucidate the Metabolism of the Preclinical Candidate TBAJ-876-A Less Toxic and More Potent Analogue of Bedaquiline
enthalten in:
Molecules (Basel, Switzerland)
| 2020
von
Choi, P.
|
Conole, D.
|
Sutherland, H.
| +6
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5
Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology
enthalten in:
Bioorganic & medicinal chemistry
| 2020
von
Sutherland, H.
|
Tong, A.
|
Choi, P.
| +7
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6
Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline
enthalten in:
Bioorganic & medicinal chemistry
| 2019
von
Blaser, A.
|
Sutherland, H.
|
Tong, A.
| +8
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7
3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel
enthalten in:
Bioorganic & medicinal chemistry
| 2019
von
Sutherland, H.
|
Tong, A.
|
Choi, P.
| +8
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8
Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles
enthalten in:
Bioorganic & medicinal chemistry
| 2018
von
Sutherland, H.
|
Tong, A.
|
Choi, P.
| +8
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9
Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units
enthalten in:
Bioorganic & medicinal chemistry letters
| 2017
von
Choi, P.
|
Sutherland, H.
|
Tong, A.
| +12
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10
6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis
enthalten in:
ACS medicinal chemistry letters
| 2017
von
Tong, A.
|
Choi, P.
|
Blaser, A.
| +12
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1
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Thema
10
Journal Article
8
Antitubercular Agents
7
78846I289Y
7
Diarylquinolines
7
bedaquiline
6
Research Support, Non-U.S. Gov't
6
Research Support, U.S. Gov't, Non-P.H.S.
5
Tuberculosis
4
ATP synthase
4
Bedaquiline
3
Drug development
3
tuberculosis
2
Bedaquiline analogues
2
CFU, colony-forming units
2
Ether-A-Go-Go Potassium Channels
2
LDA, lithium diisopropylamide
2
LORA, low oxygen recovery assay
2
LiTMP, lithium tetramethylpiperidide
2
MABA, microplate alamar blue assay
2
Potassium Channel Blockers
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2020-
5
2010-2019
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