Suchergebnisse - "Tokuriki, Nobuhiko"

PubPharm (6)

1

Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis

enthalten in: Nature communications | 2020

von Emond, S. | Petek, M. | Kay, E. | +4

2

The role of protein dynamics in the evolution of new enzyme function

enthalten in: Nature chemical biology | 2016

von Campbell, E. | Kaltenbach, M. | Correy, G. | +9

CommentIn: Nat Chem Biol. 2016 Oct 18;12(11):890-891. - PMID 27755531

3

Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity

enthalten in: PLoS genetics | 2016

von Kaltenbach, M. | Emond, S. | Hollfelder, F. | +1

4

Conformational Tinkering Drives Evolution of a Promiscuous Activity through Indirect Mutational Effects

enthalten in: Biochemistry | 2016

von Yang, G. | Hong, N. | Baier, F. | +2

5

Reverse evolution leads to genotypic incompatibility despite functional and active site convergence

enthalten in: eLife | 2015

von Kaltenbach, M. | Jackson, C. | Campbell, E. | +2

6

Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme

enthalten in: Nature communications | 2012

von Tokuriki, N. | Jackson, C. | Afriat-Jurnou, L. | +3

ErratumIn: Nat Commun. 2013;4:2678

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