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topic_facet:"Protein Kinase Inhibitors"
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/vufind/Search/Results?lookfor=%22Thomas%2C+Huw+D%22&type=Person&filter%5B%5D=topic_facet%3A%22Protein+Kinase+Inhibitors%22
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PubPharm (9)
1
Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance
enthalten in:
The Biochemical journal
| 2022
von
Hunter, J.
|
Campbell, A.
|
Butterworth, J.
| +17
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2
An Alkynylpyrimidine-Based Covalent Inhibitor That Targets a Unique Cysteine in NF-κB-Inducing Kinase
enthalten in:
Journal of medicinal chemistry
| 2021
von
Al-Khawaldeh, I.
|
Al Yasiri, M.
|
Aldred, G.
| +29
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3
Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy
enthalten in:
The Journal of clinical investigation
| 2020
von
Willoughby, C.
|
Jiang, Y.
|
Thomas, H.
| +20
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4
Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4
enthalten in:
European journal of medicinal chemistry
| 2019
von
Myers, S.
|
Miller, D.
|
Molyneux, L.
| +27
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5
Enhanced anti-tumour activity of the combination of the novel MEK inhibitor WX-554 and the novel PI3K inhibitor WX-037
enthalten in:
Cancer chemotherapy and pharmacology
| 2016
von
Haagensen, E.
|
Thomas, H.
|
Schmalix, W.
| +6
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6
Combined PI3K and CDK2 inhibition induces cell death and enhances in vivo antitumour activity in colorectal cancer
enthalten in:
British journal of cancer
| 2016
von
Beale, G.
|
Haagensen, E.
|
Thomas, H.
| +8
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7
Pre-clinical use of isogenic cell lines and tumours in vitro and in vivo for predictive biomarker discovery; impact of KRAS and PI3KCA mutation status on MEK inhibitor activity is model dependent
enthalten in:
European journal of cancer (Oxford, England : 1990)
| 2016
von
Haagensen, E.
|
Thomas, H.
|
Mudd, C.
| +5
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8
Preclinical in vitro and in vivo evaluation of the potent and specific cyclin-dependent kinase 2 inhibitor NU6102 and a water soluble prodrug NU6301
enthalten in:
European journal of cancer (Oxford, England : 1990)
| 2011
von
Thomas, H.
|
Wang, L.
|
Roche, C.
| +7
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9
Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441
enthalten in:
Cancer research
| 2006
von
Zhao, Y.
|
Thomas, H.
|
Batey, M.
| +7
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1
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Thema: Protein Kinase Inhibitors
Medienart
9
Aufsätze
8
E-Artikel
8
E-Ressourcen
1
Gedruckte Aufsätze
Zeitschriftentitel
2
European journal of cancer (Oxford, England : 1...
1
British journal of cancer
1
Cancer chemotherapy and pharmacology
1
Cancer research
1
European journal of medicinal chemistry
1
Journal of medicinal chemistry
1
The Biochemical journal
1
The Journal of clinical investigation
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Thema
9
Journal Article
Protein Kinase Inhibitors
6
Research Support, Non-U.S. Gov't
5
EC 2.7.11.1
3
Phosphoinositide-3 Kinase Inhibitors
2
Antineoplastic Agents
2
Combination
2
Cyclin-Dependent Kinase 2
2
DNA-Activated Protein Kinase
2
EC 2.7.1.1
2
EC 2.7.11.22
2
MEK
2
MTOR protein, human
2
Neoplasm Proteins
2
PI3K
2
Pyrimidines
2
TOR Serine-Threonine Kinases
1
6PLQ3CP4P3
1
8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen...
1
80168379AG
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Erscheinungszeitraum
3
2020-
5
2010-2019
1
2000-2009
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Sprache
9
Englisch
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