Suchergebnisse - "Terrett, Jack A"

PubPharm (17)

1

Discovery of TRPA1 Antagonist GDC-6599 : Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease

enthalten in: Journal of medicinal chemistry | 2024

von Terrett, J. | Ly, J. | Katavolos, P. | +53

2

Regioselective aliphatic C-H functionalization using frustrated radical pairs

enthalten in: Nature | 2023

von Lu, Z. | Ju, M. | Wang, Y. | +5

3

Simple strategy towards amide bioisosteres

enthalten in: Nature chemistry | 2022

von Huestis, M. | Terrett, J.

CommentOn: Nat Chem. 2022 Feb;14(2):160-169. - PMID 35087220

4

Exploring Electrochemical C(sp3)-H Oxidation for the Late-Stage Methylation of Complex Molecules

enthalten in: Journal of the American Chemical Society | 2022

von Novaes, L. | Ho, J. | Mao, K. | +6

5

The Direct Decarboxylative N-Alkylation of Azoles, Sulfonamides, Ureas, and Carbamates with Carboxylic Acids via Photoredox Catalysis

enthalten in: Organic letters | 2021

von Li, P. | Zbieg, J. | Terrett, J.

6

A Retrospective Look at the Impact of Binding Site Environment on the Optimization of TRPA1 Antagonists

enthalten in: ACS medicinal chemistry letters | 2021

von Villemure, E. | Terrett, J. | Larouche-Gauthier, R. | +7

7

Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists : Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy

enthalten in: Journal of medicinal chemistry | 2021

von Terrett, J. | Chen, H. | Shore, D. | +36

8

Visible-Light Photocatalysis as an Enabling Technology for Drug Discovery : A Paradigm Shift for Chemical Reactivity

enthalten in: ACS medicinal chemistry letters | 2020

von Li, P. | Terrett, J. | Zbieg, J.

9

Transient receptor potential ankyrin 1 (TRPA1) antagonists : a patent review (2015-2019)

enthalten in: Expert opinion on therapeutic patents | 2020

von Chen, H. | Terrett, J.

10

Native functionality in triple catalytic cross-coupling : sp³ C-H bonds as latent nucleophiles

enthalten in: Science (New York, N.Y.) | 2016

von Shaw, M. | Shurtleff, V. | Terrett, J. | +2

CommentIn: Science. 2016 Jun 10;352(6291):1277-8. - PMID 27284182