Suchergebnisse - "Song, Jen-Shin"

PubPharm (7)

1

Fluorine-18 isotope labeling for positron emission tomography imaging. Direct evidence for DBPR211 as a peripherally restricted CB1 inverse agonist

enthalten in: Bioorganic & medicinal chemistry | 2019

von Chang, C. | Huang, H. | Huang, J. | +6

2

Discovery of 1-(2,4-dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5-(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice

enthalten in: Journal of medicinal chemistry | 2013

von Chang, C. | Wu, C. | Song, J. | +15

3

Discovery of 1-(2,4-dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophen-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist

enthalten in: ChemMedChem | 2010

von Hung, M. | Chang, C. | Li, T. | +10

4

Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice

enthalten in: Journal of medicinal chemistry | 2009

von Wu, C. | Hung, M. | Song, J. | +16

5

Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists

enthalten in: Organic & biomolecular chemistry | 2008

von Chu, C. | Hung, M. | Hsieh, M. | +6

6

Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antagonists

enthalten in: Journal of medicinal chemistry | 2008

von Tseng, S. | Hung, M. | Chang, C. | +12

7

Design, synthesis, and biological evaluation of novel alkenylthiophenes as potent and selective CB1 cannabinoid receptor antagonists

enthalten in: Organic & biomolecular chemistry | 2008

von Tai, C. | Hung, M. | Pawar, V. | +11

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