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topic_facet:"Enzyme Inhibitors"
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PubPharm (8)
1
Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design
enthalten in:
European journal of medicinal chemistry
| 2022
von
Yeh, T.
|
Song, J.
|
Chang, P.
| +24
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2
Unique Sulfur-Aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors
enthalten in:
Journal of medicinal chemistry
| 2020
von
Peng, Y.
|
Liao, F.
|
Tseng, C.
| +17
ErratumIn: J Med Chem. 2020 Jul 9;63(13):7445. - PMID 32573230
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3
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy
enthalten in:
Bioorganic chemistry
| 2018
von
Lin, S.
|
Yeh, T.
|
Song, J.
| +22
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4
Design, Synthesis, and Evaluation of Thiazolidine-2,4-dione Derivatives as a Novel Class of Glutaminase Inhibitors
enthalten in:
Journal of medicinal chemistry
| 2017
von
Yeh, T.
|
Kuo, C.
|
Lee, Y.
| +15
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5
Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1
enthalten in:
Journal of medicinal chemistry
| 2016
von
Peng, Y.
|
Ueng, S.
|
Tseng, C.
| +16
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6
Phenyl Benzenesulfonylhydrazides Exhibit Selective Indoleamine 2,3-Dioxygenase Inhibition with Potent in Vivo Pharmacodynamic Activity and Antitumor Efficacy
enthalten in:
Journal of medicinal chemistry
| 2016
von
Lin, S.
|
Yeh, T.
|
Kuo, C.
| +20
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7
Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening
enthalten in:
Journal of medicinal chemistry
| 2015
von
Wu, J.
|
Lin, S.
|
Liao, F.
| +17
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8
Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors
enthalten in:
Bioorganic & medicinal chemistry letters
| 2014
von
Cheng, M.
|
Hung, M.
|
Song, J.
| +10
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1
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Thema: Enzyme Inhibitors
Medienart
8
Aufsätze
8
E-Artikel
8
E-Ressourcen
Zeitschriftentitel
5
Journal of medicinal chemistry
1
Bioorganic & medicinal chemistry letters
1
Bioorganic chemistry
1
European journal of medicinal chemistry
Thema
Enzyme Inhibitors
8
Journal Article
7
Research Support, Non-U.S. Gov't
6
Indoleamine-Pyrrole 2,3,-Dioxygenase
3
Antineoplastic Agents
3
Indoleamine 2,3-dioxygenase
2
IDO1 protein, human
2
Imidazoles
2
Kynurenine
2
Tryptophan
1
343-65-7
1
4-((2-(4-bromophenyl)hydrazinyl)sulfonyl)benzoi...
1
4-Bromophenylhydrazinyl benzenesulfonylphenylurea
1
8DUH1N11BX
1
Amides
1
Anti-tumor
1
Biomarkers, Tumor
1
CD3 Complex
1
CD3E protein, human
1
Cancer immunotherapy
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Erscheinungszeitraum
2
2020-
6
2010-2019
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8
Englisch
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