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PubPharm (56)
1
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis : Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5
enthalten in:
Journal of medicinal chemistry
| 2023
von
Brusa, I.
|
Sondo, E.
|
Pesce, E.
| +13
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2
Rescue by elexacaftor-tezacaftor-ivacaftor of the G1244E cystic fibrosis mutation's stability and gating defects are dependent on cell background
enthalten in:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
| 2023
von
Tomati, V.
|
Costa, S.
|
Capurro, V.
| +13
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3
Proteostasis Regulators in Cystic Fibrosis : Current Development and Future Perspectives
enthalten in:
Journal of medicinal chemistry
| 2022
von
Brusa, I.
|
Sondo, E.
|
Falchi, F.
| +3
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4
Targeting of Ubiquitin E3 Ligase RNF5 as a Novel Therapeutic Strategy in Neuroectodermal Tumors
enthalten in:
Cancers
| 2022
von
Principi, E.
|
Sondo, E.
|
Bianchi, G.
| +9
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5
Targeting the E1 ubiquitin-activating enzyme (UBA1) improves elexacaftor/tezacaftor/ivacaftor efficacy towards F508del and rare misfolded CFTR mutants
enthalten in:
Cellular and molecular life sciences : CMLS
| 2022
von
Borgo, C.
|
D'Amore, C.
|
Capurro, V.
| +6
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6
Targeting the E1 ubiquitin-activating enzyme (UBA1) improves elexacaftor/tezacaftor/ivacaftor efficacy towards F508del and rare misfolded CFTR mutants
enthalten in:
Cellular and molecular life sciences
| 2022
von
Borgo, C.
|
D’Amore, C.
|
Capurro, V.
| +6
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7
Targeting the E1 ubiquitin-activating enzyme (UBA1) improves elexacaftor/tezacaftor/ivacaftor efficacy towards F508del and rare misfolded CFTR mutants
enthalten in:
Cellular and molecular life sciences
| 2022
von
Borgo, C.
|
D’Amore, C.
|
Capurro, V.
| +6
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8
The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients : The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs
enthalten in:
International journal of molecular sciences
| 2022
von
Sondo, E.
|
Cresta, F.
|
Pastorino, C.
| +13
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9
Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment
enthalten in:
International journal of molecular sciences
| 2021
von
Capurro, V.
|
Tomati, V.
|
Sondo, E.
| +13
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10
A high-content drug screening strategy to identify protein level modulators for genetic diseases : A proof-of-principle in autosomal dominant leukodystrophy
enthalten in:
Human mutation
| 2021
von
Giorgio, E.
|
Pesce, E.
|
Pozzi, E.
| +10
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American journal of physiology. Cell physiology
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Thema
37
Journal Article
28
Research Support, Non-U.S. Gov't
23
126880-72-6
23
Cystic Fibrosis Transmembrane Conductance Regul...
12
CFTR protein, human
11
Chloride Channels
8
ANO1 protein, human
8
Anoctamin-1
8
Neoplasm Proteins
6
Benzodioxoles
6
Calcium
6
SY7Q814VUP
5
Aminophenols
5
Chlorides
5
Indoles
5
tezacaftor
4
Chloride channel
4
DNA-Binding Proteins
4
EC 2.3.2.27
4
Luminescent Proteins
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Erscheinungszeitraum
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2020-
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2010-2019
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2000-2009
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