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PubPharm (51)
1
Discovery and Mechanistic Studies of Dual-Target Hits for Carbonic Anhydrase IX and VEGFR-2 as Potential Agents for Solid Tumors : X-ray, In Vitro, In Vivo, and In Silico Investigations of Coumarin-Based Thiazoles
enthalten in:
Journal of medicinal chemistry
| 2024
von
Hefny, S.
|
El-Moselhy, T.
|
El-Din, N.
| +11
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2
Study of the binding interaction of salmon sperm DNA with nintedanib, a tyrosine kinase inhibitor using multi-spectroscopic, thermodynamic, and in silico approaches
enthalten in:
Journal of biomolecular structure & dynamics
| 2024
von
Radwan, A.
|
Salim, M.
|
Elkhoudary, M.
| +4
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3
Rosuvastatin and diosmetin inhibited the HSP70/TLR4 /NF-κB p65/NLRP3 signaling pathways and switched macrophage to M2 phenotype in a rat model of acute kidney injury induced by cisplatin
enthalten in:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
| 2024
von
Saad, H.
|
Elekhnawy, E.
|
Shaldam, M.
| +7
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4
Discovery of Novel Pyridazine-Tethered Sulfonamides as Carbonic Anhydrase II Inhibitors for the Management of Glaucoma
enthalten in:
Journal of medicinal chemistry
| 2024
von
Tawfik, H.
|
Saleh, M.
|
Ammara, A.
| +11
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5
Lead Optimization of BIBR1591 To Improve Its Telomerase Inhibitory Activity : Design and Synthesis of Novel Four Chemical Series with In Silico, In Vitro, and In Vivo Preclinical Assessments
enthalten in:
Journal of medicinal chemistry
| 2024
von
Al-Karmalawy, A.
|
Mousa, M.
|
Sharaky, M.
| +7
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6
DFT and molecular simulation validation of the binding activity of PDEδ inhibitors for repression of oncogenic k-Ras
enthalten in:
PloS one
| 2024
von
Majrashi, T.
|
Sabt, A.
|
Almahli, H.
| +7
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7
Identification of 3-(5-cyano-6-oxo-pyridin-2-yl)benzenesulfonamides as novel anticancer agents endowed with EGFR inhibitory activity
enthalten in:
Archiv der Pharmazie
| 2024
von
Shaldam, M.
|
Khalil, A.
|
Almahli, H.
| +8
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8
Tailored horseshoe-shaped nicotinonitrile scaffold as dual promising c-Met and Pim-1 inhibitors : Design, synthesis, SAR and in silico study
enthalten in:
Bioorganic chemistry
| 2024
von
Mohamady, S.
|
Khalil, A.
|
Naguib, B.
| +3
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9
Development of new thieno[2,3-d]pyrimidines as dual EGFR and STAT3 inhibitors endowed with anticancer and pro-apoptotic activities
enthalten in:
Bioorganic chemistry
| 2024
von
Elsebaie, H.
|
El-Moselhy, T.
|
El-Bastawissy, E.
| +6
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10
Identification of 3‐(5‐cyano‐6‐oxo‐pyridin‐2‐yl)benzenesulfonamides as novel anticancer agents endowed with EGFR inhibitory activity
enthalten in:
Archiv der Pharmazie
| 2024
von
Shaldam, M.
|
Khalil, A.
|
Almahli, H.
| +8
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Thema
35
Journal Article
10
Antineoplastic Agents
6
Molecular docking
5
EC 2.7.10.1
5
Protein Kinase Inhibitors
5
Quorum sensing
5
quorum sensing
4
Alzheimer’s disease
4
Anti-Bacterial Agents
4
CAMKII
4
COVID-19
4
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4
Candesartan
4
Carbonic Anhydrase IX
4
Carbonic Anhydrase Inhibitors
4
Chloroquine
4
Chronotherapy
4
Domperidone
4
Drug repurposing
4
EC 4.2.1.1
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Erscheinungszeitraum
10
2024
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2023
14
2022
13
2021
7
2020
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