Suchergebnisse - "Selkoe, Dennis"

PubPharm (55)

1

Identification of the Aβ37/42 peptide ratio in CSF as an improved Aβ biomarker for Alzheimer's disease

enthalten in: Alzheimer's & dementia : the journal of the Alzheimer's Association | 2023

von Liu, L. | Lauro, B. | He, A. | +8

2

Treatments for Alzheimer's disease emerge

enthalten in: Science (New York, N.Y.) | 2021

von Selkoe, D.

CommentIn: Science. 2021 Oct 29;374(6567):544-545. - PMID 34709898

3

Hydrophilic loop 1 of Presenilin-1 and the APP GxxxG transmembrane motif regulate γ-secretase function in generating Alzheimer-causing Aβ peptides

enthalten in: The Journal of biological chemistry | 2021

von Liu, L. | Lauro, B. | Wolfe, M. | +1

4

Multiple BACE1 inhibitors abnormally increase the BACE1 protein level in neurons by prolonging its half-life

enthalten in: Alzheimer's & dementia : the journal of the Alzheimer's Association | 2019

von Liu, L. | Lauro, B. | Ding, L. | +3

5

β-secretase inhibitors for Alzheimer's disease : heading in the wrong direction?

enthalten in: The Lancet. Neurology | 2019

von Selkoe, D.

6

A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor

enthalten in: The Journal of cell biology | 2019

von Liu, L. | Ding, L. | Rovere, M. | +2

7

The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase

enthalten in: eLife | 2016

von Bolduc, D. | Montagna, D. | Seghers, M. | +2

CommentIn: Elife. 2016 Aug 31;5:. - PMID 27580373

8

Part 1 : Notch-sparing γ-secretase inhibitors: The identification of novel naphthyl and benzofuranyl amide analogs

enthalten in: Bioorganic & medicinal chemistry letters | 2016

von Lu, D. | Wei, H. | Zhang, J. | +6

9

Part 2. Notch-sparing γ-secretase inhibitors : The study of novel γ-amino naphthyl alcohols

enthalten in: Bioorganic & medicinal chemistry letters | 2016

von Wei, H. | Lu, D. | Sun, V. | +7

10

Part 3 : Notch-sparing γ-secretase inhibitors: SAR studies of 2-substituted aminopyridopyrimidinones

enthalten in: Bioorganic & medicinal chemistry letters | 2016

von Zhang, J. | Lu, D. | Wei, H. | +4

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