Suchergebnisse - "Scialis, Renato J."

PubPharm (38)

1

Mechanistic investigation of liver injury induced by BMS-932481, an experimental ɣ-secretase modulator

enthalten in: Toxicological sciences : an official journal of the Society of Toxicology | 2023

von Zhuo, X. | Howell, B. | Shen, H. | +12

2

Evaluation of Hepatic Uptake of OATP1B Substrates by Short Term-Cultured Plated Human Hepatocytes : Comparison With Isolated Suspended Hepatocytes

enthalten in: Journal of pharmaceutical sciences | 2021

von Yoshikado, T. | Lee, W. | Toshimoto, K. | +15

3

Cell-to-Medium Concentration Ratio Overshoot in the Uptake of Statins by Human Hepatocytes in Suspension, but Not in Monolayer : Kinetic Analysis Suggesting a Partial Loss of Functional OATP1Bs

enthalten in: The AAPS journal | 2020

von Lee, W. | Koyama, S. | Morita, K. | +13

4

Cell-to-Medium Concentration Ratio Overshoot in the Uptake of Statins by Human Hepatocytes in Suspension, but Not in Monolayer: Kinetic Analysis Suggesting a Partial Loss of Functional OATP1Bs

enthalten in: The AAPS journal | 2020

von Lee, W. | Koyama, S. | Morita, K. | +13

5

Cell-to-Medium Concentration Ratio Overshoot in the Uptake of Statins by Human Hepatocytes in Suspension, but Not in Monolayer: Kinetic Analysis Suggesting a Partial Loss of Functional OATP1Bs

enthalten in: AAPS PharmSci | 2020

von Lee, W. | Koyama, S. | Morita, K. | +13

6

The modulation of transcriptional expression and inhibition of multidrug resistance associated protein 4 (MRP4) by analgesics and their primary metabolites

enthalten in: Current research in toxicology | 2020

von Scialis, R. | Ghanem, C. | Manautou, J.

7

Identification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its Metabolites

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2019

von Scialis, R. | Aleksunes, L. | Csanaky, I. | +2

8

Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc : Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2019

von Kimoto, E. | Vourvahis, M. | Scialis, R. | +3

9

Xenobiotic Transporters in the Kidney : Function and Role in Toxicity

enthalten in: Seminars in nephrology | 2019

von Shen, H. | Scialis, R. | Lehman-McKeeman, L.

10

Transporter-Mediated Disposition, Clinical Pharmacokinetics and Cholestatic Potential of Glyburide and Its Primary Active Metabolites

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2017

von Li, R. | Bi, Y. | Vildhede, A. | +6