Suchergebnisse - "Schmidt, Christopher J"

PubPharm (108)

1

First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B

enthalten in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine | 2022

von Wakabayashi, Y. | Stenkrona, P. | Arakawa, R. | +22

2

PDE10A Inhibitors-Clinical Failure or Window Into Antipsychotic Drug Action?

enthalten in: Frontiers in neuroscience | 2020

von Menniti, F. | Chappie, T. | Schmidt, C.

3

Phosphodiesterase 10A Inhibitor Monotherapy Is Not an Effective Treatment of Acute Schizophrenia

enthalten in: Journal of clinical psychopharmacology | 2019

von Walling, D. | Banerjee, A. | Dawra, V. | +3

4

A Proof-of-Concept Study Evaluating the Phosphodiesterase 10A Inhibitor PF-02545920 in the Adjunctive Treatment of Suboptimally Controlled Symptoms of Schizophrenia

enthalten in: Journal of clinical psychopharmacology | 2019

von DeMartinis, N. | Lopez, R. | Pickering, E. | +4

5

In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [18F]MNI-659

enthalten in: Brain research | 2019

von Svedberg, M. | Varnäs, K. | Varrone, A. | +9

6

Phosphodiesterase 9A in Brain Regulates cGMP Signaling Independent of Nitric-Oxide

enthalten in: Frontiers in neuroscience | 2019

von Harms, J. | Menniti, F. | Schmidt, C.

7

Correction to Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor

enthalten in: Journal of medicinal chemistry | 2018

von Helal, C. | Arnold, E. | Boyden, T. | +25

ErratumFor: J Med Chem. 2017 Jul 13;60(13):5673-5698. - PMID 28574706

8

Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate

enthalten in: Journal of medicinal chemistry | 2018

von Helal, C. | Arnold, E. | Boyden, T. | +26

9

The isozyme selective phosphodiesterase-4 inhibitor, ABI-4, attenuates the effects of lipopolysaccharide in human cells and rodent models of peripheral and CNS inflammation

enthalten in: Brain, behavior, and immunity | 2017

von Hedde, J. | Hanks, A. | Schmidt, C. | +1

10

Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor

enthalten in: Journal of medicinal chemistry | 2017

von Helal, C. | Arnold, E. | Boyden, T. | +24

ErratumIn: J Med Chem. 2018 Apr 26;61(8):3753. - PMID 29624389

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