Suchergebnisse - "Rochais, Christophe"

PubPharm (11)

1

Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation

enthalten in: Molecules (Basel, Switzerland) | 2022

von Malek, R. | Simakov, A. | Davis, A. | +10

2

Development of Novel Potential Pleiotropic Compounds of Interest in Alzheimer's Disease Treatment through Rigidification Strategy

enthalten in: Molecules (Basel, Switzerland) | 2021

von Lecoutey, C. | Legay, R. | Davis, A. | +3

3

Pleiotropic prodrugs : Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer's disease

enthalten in: European journal of medicinal chemistry | 2021

von Toublet, F. | Lalut, J. | Hatat, B. | +10

4

First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease

enthalten in: Molecules (Basel, Switzerland) | 2020

von Guieu, B. | Lecoutey, C. | Legay, R. | +6

5

Rational design of novel benzisoxazole derivatives with acetylcholinesterase inhibitory and serotoninergic 5-HT4 receptors activities for the treatment of Alzheimer's disease

enthalten in: Scientific reports | 2020

von Lalut, J. | Payan, H. | Davis, A. | +6

6

Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease

enthalten in: Molecules (Basel, Switzerland) | 2019

von Toublet, F. | Lecoutey, C. | Lalut, J. | +10

7

Novel multitarget-directed ligands targeting acetylcholinesterase and σ1 receptors as lead compounds for treatment of Alzheimer's disease : Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase

enthalten in: European journal of medicinal chemistry | 2019

von Lalut, J. | Santoni, G. | Karila, D. | +9

8

Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease : the design of donecopride

enthalten in: Journal of medicinal chemistry | 2015

von Rochais, C. | Lecoutey, C. | Gaven, F. | +17

9

Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment

enthalten in: Proceedings of the National Academy of Sciences of the United States of America | 2014

von Lecoutey, C. | Hedou, D. | Freret, T. | +13

10

Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice

enthalten in: Behavioural brain research | 2012

von Freret, T. | Bouet, V. | Quiedeville, A. | +4