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topic_facet:"Pyrroles"
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PubPharm (6)
1
Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy
enthalten in:
Molecular cancer therapeutics
| 2019
von
Dekhne, A.
|
Shah, K.
|
Ducker, G.
| +22
ErratumIn: Mol Cancer Ther. 2023 Feb 1;22(2):287. - PMID 36602953
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2
Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3- d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis
enthalten in:
Journal of medicinal chemistry
| 2018
von
Ravindra, M.
|
Wallace-Povirk, A.
|
Karim, M.
| +9
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3
Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis
enthalten in:
Journal of medicinal chemistry
| 2016
von
Golani, L.
|
Wallace-Povirk, A.
|
Deis, S.
| +17
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4
6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors
enthalten in:
Journal of medicinal chemistry
| 2015
von
Wang, L.
|
Wallace, A.
|
Raghavan, S.
| +14
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5
Therapeutic targeting malignant mesothelioma with a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate via its selective uptake by the proton-coupled folate transporter
enthalten in:
Cancer chemotherapy and pharmacology
| 2013
von
Cherian, C.
|
Kugel Desmoulin, S.
|
Wang, L.
| +7
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6
Functional loss of the reduced folate carrier enhances the antitumor activities of novel antifolates with selective uptake by the proton-coupled folate transporter
enthalten in:
Molecular pharmacology
| 2012
von
Desmoulin, S.
|
Wang, L.
|
Polin, L.
| +7
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1
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Thema: Pyrroles
Medienart
6
Aufsätze
6
E-Artikel
6
E-Ressourcen
Zeitschriftentitel
3
Journal of medicinal chemistry
1
Cancer chemotherapy and pharmacology
1
Molecular cancer therapeutics
1
Molecular pharmacology
Thema
6
Journal Article
6
Pyrimidines
Pyrroles
6
Research Support, N.I.H., Extramural
5
Antineoplastic Agents
5
Folic Acid Antagonists
5
Proton-Coupled Folate Transporter
5
Research Support, Non-U.S. Gov't
3
EC 2.1.2.2
3
Folate Receptor 1
3
Phosphoribosylglycinamide Formyltransferase
2
Purine Nucleotides
2
Thiophenes
1
04Q9AIZ7NO
1
25513-46-6
1
7440-44-0
1
Carbon
1
Folate Receptor 2
1
K8CXK5Q32L
1
Pemetrexed
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2019
1
2018
1
2016
1
2015
1
2013
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2012
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