Suchergebnisse - "Polin, Lisa"

PubPharm (16)

1

Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment

enthalten in: Scientific reports | 2022

von Wallace-Povirk, A. | Rubinsak, L. | Malysa, A. | +13

2

The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML

enthalten in: Blood cancer journal | 2021

von Qiao, X. | Ma, J. | Knight, T. | +14

3

ONC201 induces the unfolded protein response (UPR) in high- and low-grade ovarian carcinoma cell lines and leads to cell death regardless of platinum sensitivity

enthalten in: Cancer medicine | 2021

von Rumman, M. | Buck, S. | Polin, L. | +3

4

The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia

enthalten in: Haematologica | 2021

von Li, X. | Su, Y. | Hege, K. | +15

5

Antileukemic activity and mechanism of action of the novel PI3K and histone deacetylase dual inhibitor CUDC-907 in acute myeloid leukemia

enthalten in: Haematologica | 2019

von Li, X. | Su, Y. | Madlambayan, G. | +13

6

Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy

enthalten in: Molecular cancer therapeutics | 2019

von Dekhne, A. | Shah, K. | Ducker, G. | +22

ErratumIn: Mol Cancer Ther. 2023 Feb 1;22(2):287. - PMID 36602953

7

Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis

enthalten in: Journal of medicinal chemistry | 2018

von Ravindra, M. | Wilson, M. | Tong, N. | +9

8

Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3- d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis

enthalten in: Journal of medicinal chemistry | 2018

von Ravindra, M. | Wallace-Povirk, A. | Karim, M. | +9

9

Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis

enthalten in: Journal of medicinal chemistry | 2016

von Golani, L. | Wallace-Povirk, A. | Deis, S. | +17

10

Targeting Nonsquamous Nonsmall Cell Lung Cancer via the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]Pyrimidine Thienoyl Antifolates

enthalten in: Molecular pharmacology | 2016

von Wilson, M. | Hou, Z. | Yang, S. | +7