Suchergebnisse - "Polin, Lisa"

PubPharm (11)

1

Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis

enthalten in: Journal of medicinal chemistry | 2018

von Ravindra, M. | Wilson, M. | Tong, N. | +9

2

Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3- d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis

enthalten in: Journal of medicinal chemistry | 2018

von Ravindra, M. | Wallace-Povirk, A. | Karim, M. | +9

3

Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]pyrimidine Antifolates

enthalten in: Molecular cancer therapeutics | 2017

von Hou, Z. | Gattoc, L. | O'Connor, C. | +10

4

Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis

enthalten in: Journal of medicinal chemistry | 2016

von Golani, L. | Wallace-Povirk, A. | Deis, S. | +17

5

Targeting Nonsquamous Nonsmall Cell Lung Cancer via the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]Pyrimidine Thienoyl Antifolates

enthalten in: Molecular pharmacology | 2016

von Wilson, M. | Hou, Z. | Yang, S. | +7

6

6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors

enthalten in: Journal of medicinal chemistry | 2015

von Wang, L. | Wallace, A. | Raghavan, S. | +14

7

Therapeutic targeting malignant mesothelioma with a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate via its selective uptake by the proton-coupled folate transporter

enthalten in: Cancer chemotherapy and pharmacology | 2013

von Cherian, C. | Kugel Desmoulin, S. | Wang, L. | +7

8

Functional loss of the reduced folate carrier enhances the antitumor activities of novel antifolates with selective uptake by the proton-coupled folate transporter

enthalten in: Molecular pharmacology | 2012

von Desmoulin, S. | Wang, L. | Polin, L. | +7

9

Therapeutic targeting of a novel 6-substituted pyrrolo [2,3-d]pyrimidine thienoyl antifolate to human solid tumors based on selective uptake by the proton-coupled folate transporter

enthalten in: Molecular pharmacology | 2011

von Kugel Desmoulin, S. | Wang, L. | Hales, E. | +8

10

Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide ribonucleotide formyltransferase

enthalten in: Journal of medicinal chemistry | 2011

von Wang, L. | Desmoulin, S. | Cherian, C. | +11