Suchergebnisse - "Polin, Lisa"

PubPharm (35)

1

Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment

enthalten in: Scientific reports | 2022

von Wallace-Povirk, A. | Rubinsak, L. | Malysa, A. | +13

2

ONC201 induces the unfolded protein response (UPR) in high- and low-grade ovarian carcinoma cell lines and leads to cell death regardless of platinum sensitivity

enthalten in: Cancer medicine | 2021

von Rumman, M. | Buck, S. | Polin, L. | +3

3

Antagonizing binding of cell cycle and apoptosis regulatory protein 1 (CARP-1) to the NEMO/IKKγ protein enhances the anticancer effect of chemotherapy

enthalten in: The Journal of biological chemistry | 2020

von Venkatesh, J. | Sekhar, S. | Cheriyan, V. | +7

4

Inhibition of CDK9 by voruciclib synergistically enhances cell death induced by the Bcl-2 selective inhibitor venetoclax in preclinical models of acute myeloid leukemia

enthalten in: Signal transduction and targeted therapy | 2020

von Luedtke, D. | Su, Y. | Ma, J. | +10

5

Antileukemic activity and mechanism of action of the novel PI3K and histone deacetylase dual inhibitor CUDC-907 in acute myeloid leukemia

enthalten in: Haematologica | 2019

von Li, X. | Su, Y. | Madlambayan, G. | +13

6

Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy

enthalten in: Molecular cancer therapeutics | 2019

von Dekhne, A. | Shah, K. | Ducker, G. | +22

ErratumIn: Mol Cancer Ther. 2023 Feb 1;22(2):287. - PMID 36602953

7

Disulfiram and BKM120 in Combination with Chemotherapy Impede Tumor Progression and Delay Tumor Recurrence in Tumor Initiating Cell-Rich TNBC

enthalten in: Scientific reports | 2019

von Wu, L. | Meng, F. | Dong, L. | +9

8

Tumor hypoxia directed multimodal nanotherapy for overcoming drug resistance in renal cell carcinoma and reprogramming macrophages

enthalten in: Biomaterials | 2018

von Alsaab, H. | Sau, S. | Alzhrani, R. | +5

9

Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis

enthalten in: Journal of medicinal chemistry | 2018

von Ravindra, M. | Wilson, M. | Tong, N. | +9

10

Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3- d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis

enthalten in: Journal of medicinal chemistry | 2018

von Ravindra, M. | Wallace-Povirk, A. | Karim, M. | +9