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topic_facet:"Antineoplastic Agents"
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PubPharm (7)
1
Application of the model-informed drug development paradigm to datopotamab deruxtecan dose selection for late-stage development
enthalten in:
CPT: pharmacometrics & systems pharmacology
| 2024
von
Lu, Y.
|
Liang, S.
|
Hong, Y.
| +9
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2
Activation of ErbB2- ErbB3 signaling pathway supports potential therapeutic activity of ErbB inhibitors in AT/RT
enthalten in:
Journal of neuro-oncology
| 2014
von
Sredni, S.
|
Patel, K.
|
D'Almeida Costa, F.
| +2
CommentOn: J Neurooncol. 2013 Sep;114(2):173-9. - PMID 23836190
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3
PR-104 plus sorafenib in patients with advanced hepatocellular carcinoma
enthalten in:
Cancer chemotherapy and pharmacology
| 2011
von
Abou-Alfa, G.
|
Chan, S.
|
Lin, C.
| +9
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4
A combined pharmacokinetic model for the hypoxia-targeted prodrug PR-104A in humans, dogs, rats and mice predicts species differences in clearance and toxicity
enthalten in:
Cancer chemotherapy and pharmacology
| 2011
von
Patel, K.
|
Choy, S.
|
Hicks, K.
| +3
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5
Reductive metabolism of the dinitrobenzamide mustard anticancer prodrug PR-104 in mice
enthalten in:
Cancer chemotherapy and pharmacology
| 2011
von
Gu, Y.
|
Guise, C.
|
Patel, K.
| +8
ErratumIn: Cancer Chemother Pharmacol. 2011 May;67(5):1209 Lie, Jie [corrected to Li, Jie]
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6
Oxygen dependence and extravascular transport of hypoxia-activated prodrugs : comparison of the dinitrobenzamide mustard PR-104A and tirapazamine
enthalten in:
International journal of radiation oncology, biology, physics
| 2007
von
Hicks, K.
|
Myint, H.
|
Patterson, A.
| +4
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7
Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2007
von
Patterson, A.
|
Ferry, D.
|
Edmunds, S.
| +10
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1
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Thema: Antineoplastic Agents
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7
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Cancer chemotherapy and pharmacology
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Journal of neuro-oncology
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Thema
Antineoplastic Agents
5
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Nitrogen Mustard Compounds
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Research Support, Non-U.S. Gov't
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PR-104
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PR-104A
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Clinical Trial, Phase I
1
1UD32YR59G
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25X51I8RD4
1
3-Hydroxysteroid Dehydrogenases
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9007-49-2
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9ZOQ3TZI87
1
AKR1C3 protein, human
1
Aldo-Keto Reductase Family 1 Member C3
1
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Blood Proteins
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2020-
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2010-2019
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