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PubPharm (201)
1
First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease
enthalten in:
Journal of medicinal chemistry
| 2024
von
Pyka, P.
|
Haberek, W.
|
Więcek, M.
| +33
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2
Hydrophobicity modulation via the substituents at positions 2 and 4 of 1,3,5-triazine to enhance therapeutic ability against Alzheimer's disease for potent serotonin 5-HT6R agents
enthalten in:
European journal of medicinal chemistry
| 2023
von
Sudoł-Tałaj, S.
|
Kucwaj-Brysz, K.
|
Podlewska, S.
| +17
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3
Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease
enthalten in:
European journal of medicinal chemistry
| 2023
von
Czarnota-Łydka, K.
|
Sudoł-Tałaj, S.
|
Kucwaj-Brysz, K.
| +22
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4
Synthesis, computational simulations and biological evaluation of new dual 5HT1A/5HT7 receptor ligands based on purine-2,6-dione scaffold
enthalten in:
Bioorganic chemistry
| 2023
von
Zagórska, A.
|
Partyka, A.
|
Jastrzębska-Więsek, M.
| +8
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5
HBK-15, a Multimodal Compound, Showed an Anxiolytic-Like Effect in Rats
enthalten in:
Neurochemical research
| 2023
von
Lustyk, K.
|
Sałaciak, K.
|
Jakubczyk, M.
| +5
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6
Hybrid molecules combining GABA-A and serotonin 5-HT6 receptors activity designed to tackle neuroinflammation associated with depression
enthalten in:
European journal of medicinal chemistry
| 2023
von
Marcinkowska, M.
|
Mordyl, B.
|
Fajkis-Zajaczkowska, N.
| +14
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7
Selective 5-HT6 Receptor Ligands (Agonist and Antagonist) Show Different Effects on Antipsychotic Drug-Induced Metabolic Dysfunctions in Rats
enthalten in:
Pharmaceuticals (Basel, Switzerland)
| 2023
von
Partyka, A.
|
Górecka, K.
|
Gdula-Argasińska, J.
| +3
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8
Variation in the gene encoding the co-inhibitory molecule BTLA is associated with survival in patients treated for clear cell renal carcinoma - results of a prospective cohort study
enthalten in:
Archives of medical science : AMS
| 2023
von
Tupikowski, K.
|
Partyka, A.
|
Pawlak, E.
| +5
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9
Prevalence of uncoupling protein one genetic polymorphisms and their relationship with cardiovascular and metabolic health
enthalten in:
bioRxiv.org
| 2022
von
Dinas, P.
|
Nintou, E.
|
Vliora, M.
| +26
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10
HBK-15, a Multimodal Compound, Showed an Anxiolytic-Like Effect in Rats
enthalten in:
Neurochemical research
| 2022
von
Lustyk, K.
|
Sałaciak, K.
|
Jakubczyk, M.
| +5
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Thema
98
Journal Article
50
Research Support, Non-U.S. Gov't
47
Receptors, Serotonin
35
Antidepressive Agents
26
Depression
21
serotonin 7 receptor
20
112692-38-3
20
Receptor, Serotonin, 5-HT1A
18
Antipsychotic Agents
18
serotonin 6 receptor
17
5-HT
17
Serotonin
16
Anti-Anxiety Agents
16
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16
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15
333DO1RDJY
15
Piperazines
13
EMD386088
12
Anxiety
11
Forced swim test
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Erscheinungszeitraum
34
2020-
165
2010-2019
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2000-2009
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