Suchergebnisse - "Palmer, Brian D"

PubPharm (124)

51

Synthesis and structure-activity studies of biphenyl analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)

enthalten in: Journal of medicinal chemistry | 2010

von Palmer, B. | Thompson, A. | Sutherland, H. | +7

52

Synthesis, reduction potentials, and antitubercular activity of ring A/B analogues of the bioreductive drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)

enthalten in: Journal of medicinal chemistry | 2009

von Thompson, A. | Blaser, A. | Anderson, R. | +5

53

Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells

enthalten in: Molecular cancer therapeutics | 2009

von Parsels, L. | Morgan, M. | Tanska, D. | +8

54

Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells

enthalten in: Molecular cancer therapeutics | 2009

von Parsels, L. | Morgan, M. | Tanska, D. | +8

55

Release of nitrite from the antitubercular nitroimidazole drug PA-824 and analogues upon one-electron reduction in protic, non-aqueous solvent

enthalten in: Organic & biomolecular chemistry | 2009

von Maroz, A. | Shinde, S. | Franzblau, S. | +4

56

Intermediates in the reduction of the antituberculosis drug PA-824, (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine, in aqueous solution

enthalten in: Organic & biomolecular chemistry | 2008

von Anderson, R. | Shinde, S. | Maroz, A. | +3

57

Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases

enthalten in: European journal of medicinal chemistry | 2008

von Smaill, J. | Baker, E. | Booth, R. | +13

58

Synthesis and structure–activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases

enthalten in: European journal of medicinal chemistry | 2008

von Smaill, J. | Baker, E. | Booth, R. | +13

59

Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases

enthalten in: Bioorganic & medicinal chemistry letters | 2008

von Smaill, J. | Lee, H. | Palmer, B. | +7

60

Synthesis and structure–activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,- 6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases

enthalten in: Bioorganic & medicinal chemistry letters | 2008

von Smaill, J. | Lee, H. | Palmer, B. | +7