Suchergebnisse - "Palmer, Brian D"

PubPharm (11)

1

6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]thiazoles : Facile synthesis and comparative appraisal against tuberculosis and neglected tropical diseases

enthalten in: Bioorganic & medicinal chemistry letters | 2017

von Thompson, A. | Blaser, A. | Palmer, B. | +10

2

Biarylmethoxy 2-nitroimidazooxazine antituberculosis agents : Effects of proximal ring substitution and linker reversal on metabolism and efficacy

enthalten in: Bioorganic & medicinal chemistry letters | 2015

von Thompson, A. | Blaser, A. | Palmer, B. | +5

3

Synthesis and structure-activity relationships for extended side chain analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)

enthalten in: Journal of medicinal chemistry | 2015

von Palmer, B. | Sutherland, H. | Blaser, A. | +7

4

Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)

enthalten in: Journal of medicinal chemistry | 2012

von Blaser, A. | Palmer, B. | Sutherland, H. | +7

5

Synthesis and structure-activity relationships of varied ether linker analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5h-imidazo[2,1-b][1,3]oxazine (PA-824)

enthalten in: Journal of medicinal chemistry | 2011

von Thompson, A. | Sutherland, H. | Palmer, B. | +7

6

Synthesis and structure-activity relationships of aza- and diazabiphenyl analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)

enthalten in: Journal of medicinal chemistry | 2010

von Kmentova, I. | Sutherland, H. | Palmer, B. | +7

7

The nitroimidazooxazines (PA-824 and analogs) : structure-activity relationship and mechanistic studies

enthalten in: Future medicinal chemistry | 2010

von Denny, W. | Palmer, B.

8

Release of nitrite from the antitubercular nitroimidazole drug PA-824 and analogues upon one-electron reduction in protic, non-aqueous solvent

enthalten in: Organic & biomolecular chemistry | 2010

von Maroz, A. | Shinde, S. | Franzblau, S. | +4

9

Synthesis and structure-activity studies of biphenyl analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)

enthalten in: Journal of medicinal chemistry | 2010

von Palmer, B. | Thompson, A. | Sutherland, H. | +7

10

Synthesis, reduction potentials, and antitubercular activity of ring A/B analogues of the bioreductive drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)

enthalten in: Journal of medicinal chemistry | 2009

von Thompson, A. | Blaser, A. | Anderson, R. | +5