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PubPharm (15)
1
Unveiling the intra-tumor fate of trastuzumab deruxtecan in a xenograft model to support its mechanism of action
enthalten in:
Drug metabolism and pharmacokinetics
| 2024
von
Nagai, Y.
|
Oitate, M.
|
Shibayama, T.
| +2
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2
A splice-switching oligonucleotide treatment ameliorates glycogen storage disease type 1a in mice with G6PC c.648G>T
enthalten in:
The Journal of clinical investigation
| 2023
von
Ito, K.
|
Tajima, G.
|
Kamisato, C.
| +22
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3
Transition of average drug-to-antibody ratio of trastuzumab deruxtecan in systemic circulation in monkeys using a hybrid affinity capture liquid chromatography-tandem mass spectrometry
enthalten in:
Biopharmaceutics & drug disposition
| 2023
von
Habara, H.
|
Okamoto, H.
|
Nagai, Y.
| +3
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4
A Quantitative Prediction Method for the Human Pharmacokinetics of Fc-Fusion Proteins
enthalten in:
European journal of drug metabolism and pharmacokinetics
| 2023
von
Yokoyama, M.
|
Suzuki, E.
|
Oitate, M.
| +1
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5
Pharmacokinetics of trastuzumab deruxtecan (T-DXd), a novel anti-HER2 antibody-drug conjugate, in HER2-positive tumour-bearing mice
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2020
von
Okamoto, H.
|
Oitate, M.
|
Hagihara, K.
| +4
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6
Comprehensive preclinical pharmacokinetic evaluations of trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, in cynomolgus monkeys
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2019
von
Nagai, Y.
|
Oitate, M.
|
Shiozawa, H.
| +1
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7
DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2016
von
Ogitani, Y.
|
Aida, T.
|
Hagihara, K.
| +13
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8
Wide application of a novel topoisomerase I inhibitor-based drug conjugation technology
enthalten in:
Bioorganic & medicinal chemistry letters
| 2016
von
Ogitani, Y.
|
Abe, Y.
|
Iguchi, T.
| +12
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9
Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity
enthalten in:
Cancer science
| 2016
von
Ogitani, Y.
|
Hagihara, K.
|
Oitate, M.
| +2
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10
Prediction of human plasma concentration-time profiles of monoclonal antibodies from monkey data by a species-invariant time method
enthalten in:
Drug metabolism and pharmacokinetics
| 2012
von
Oitate, M.
|
Nakayama, S.
|
Ito, T.
| +3
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Thema: Journal Article
Medienart
15
Aufsätze
12
E-Artikel
12
E-Ressourcen
3
Gedruckte Aufsätze
Zeitschriftentitel
3
Drug metabolism and pharmacokinetics
2
Drug metabolism and disposition: the biological...
2
Xenobiotica; the fate of foreign compounds in b...
1
Antimicrobial agents and chemotherapy
1
Bioorganic & medicinal chemistry letters
1
Biopharmaceutics & drug disposition
1
Cancer science
1
Clinical cancer research : an official journal ...
1
European journal of drug metabolism and pharmac...
1
The Journal of clinical investigation
1
The Journal of pharmacology and experimental th...
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Thema
Journal Article
5
Antibodies, Monoclonal, Humanized
5
Immunoconjugates
5
Topoisomerase I Inhibitors
4
5384HK7574
4
Camptothecin
4
P188ANX8CK
4
Trastuzumab
4
XT3Z54Z28A
4
trastuzumab deruxtecan
3
0QTW8Z7MCR
3
9007-58-3
3
Ado-Trastuzumab Emtansine
3
Antibodies, Monoclonal
3
EC 2.7.10.1
3
ERBB2 protein, human
3
Elastin
3
Lactones
3
Receptor, ErbB-2
3
SE2KH7T06F
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Erscheinungszeitraum
5
2020-
6
2010-2019
4
2000-2009
Erscheinungsjahr(e)
Von:
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Sprache
15
Englisch
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