Suchergebnisse - "Off-target toxicity"

PubPharm (37)

1

Inhibitory CARs fail to protect from immediate T cell cytotoxicity

enthalten in: Molecular therapy : the journal of the American Society of Gene Therapy | 2024

von Funk, M. | Heller, G. | Waidhofer-Söllner, P. | +2

2

Cooperative CAR targeting to selectively eliminate AML and minimize escape

enthalten in: Cancer cell | 2023

von Haubner, S. | Mansilla-Soto, J. | Nataraj, S. | +11

CommentIn: Cancer Cell. 2023 Nov 13;41(11):1841-1843. - PMID 37832553

3

Challenges and solutions for therapeutic TCR-based agents

enthalten in: Immunological reviews | 2023

von Malviya, M. | Aretz, Z. | Molvi, Z. | +5

4

Targeting and cytotoxicity of chimeric antigen receptor T cells grafted with PD1 extramembrane domain

enthalten in: Experimental hematology & oncology | 2023

von Zhang, A. | Wang, S. | Sun, Y. | +15

5

Industry perspective on the nonclinical safety assessment of heterobifunctional degraders

enthalten in: Drug discovery today | 2023

von Hemkens, M. | Stamp, K. | Loberg, L. | +2

6

Off target toxicities and links with physicochemical properties of medicinal products, including antibiotics, oligonucleotides, lipid nanoparticles (with cationic and/or anionic charges). Data review suggests an emerging pattern

enthalten in: Toxicology letters | 2023

von Gould, S. | Templin, M.

7

Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics

enthalten in: European journal of nuclear medicine and molecular imaging | 2023

von Lucaroni, L. | Georgiev, T. | Prodi, E. | +9

CommentIn: Eur J Nucl Med Mol Imaging. 2023 Aug;50(10):2944-2946. - PMID 37191680

8

CrossDome : an interactive R package to predict cross-reactivity risk using immunopeptidomics databases

enthalten in: Frontiers in immunology | 2023

von Fonseca, A. | Antunes, D.

9

Targeting and cytotoxicity of chimeric antigen receptor T cells grafted with PD1 extramembrane domain

in: Experimental Hematology & Oncology | 2023

von Ang Zhang | Shenyu Wang | Yao Sun | +15

10

Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics

enthalten in: European journal of nuclear medicine and molecular imaging | 2022

von Lucaroni, L. | Georgiev, T. | Prodi, E. | +9