Suchergebnisse - "Minegishi, Genki"

PubPharm (10)

1

Induction of hepatic CYP3A4 expression by cholesterol and cholic acid : Alterations of gene expression, microsomal activity, and pharmacokinetics

enthalten in: Pharmacology research & perspectives | 2024

von Minegishi, G. | Kobayashi, Y. | Fujikura, M. | +3

2

Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse Cyp2c and Cyp3a Genes

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2023

von Kobayashi, K. | Minegishi, G. | Kuriyama, N. | +4

3

Influence of MDR1 gene polymorphism (2677G>T) on expression and function of P-glycoprotein at the blood-brain barrier : utilizing novel P-glycoprotein humanized mice with mutation

enthalten in: Pharmacogenetics and genomics | 2022

von Yamasaki, Y. | Moriwaki, T. | Ogata, S. | +8

4

Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure

enthalten in: Cell metabolism | 2022

von Katsumura, S. | Siddiqui, N. | Goldsmith, M. | +13

CommentIn: Nat Rev Endocrinol. 2022 Jul;18(7):392. - PMID 35523890

5

In vivo evaluation of intestinal human CYP3A inhibition by macrolide antibiotics in CYP3A-humanised mice

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2021

von Minegishi, G. | Kazuki, Y. | Nitta, S. | +3

6

In vivoevaluation of intestinal human CYP3A inhibition by macrolide antibiotics in CYP3A-humanised mice

enthalten in: Xenobiotica | 2021

von Minegishi, G. | Kazuki, Y. | Nitta, S. | +3

7

Comparison of the hepatic metabolism of triazolam in wild-type andCyp3a-knockout mice for understanding CYP3A-mediated metabolism inCYP3A-humanised mice in vivo

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2019

von Minegishi, G. | Kazuki, Y. | Yamasaki, Y. | +4

8

CYP3A4 Induction in the Liver and Intestine of Pregnane X Receptor/CYP3A-Humanized Mice : Approaches by Mass Spectrometry Imaging and Portal Blood Analysis

enthalten in: Molecular pharmacology | 2019

von Kobayashi, K. | Kuze, J. | Abe, S. | +8

9

Comparison of the hepatic metabolism of triazolam in wild-type andCyp3a-knockout mice for understanding CYP3A-mediated metabolism inCYP3A-humanised micein vivo

enthalten in: Xenobiotica | 2019

von Minegishi, G. | Kazuki, Y. | Yamasaki, Y. | +4

10

Characterization of P-Glycoprotein Humanized Mice Generated by Chromosome Engineering Technology : Its Utility for Prediction of Drug Distribution to the Brain in Humans

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2018

von Yamasaki, Y. | Kobayashi, K. | Okuya, F. | +13

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