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PubPharm (35)
1
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PF-06817024 in Healthy Participants, Participants with Chronic Rhinosinusitis with Nasal Polyps, and Participants with Atopic Dermatitis : A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study
enthalten in:
Journal of clinical pharmacology
| 2024
von
Danto, S.
|
Tsamandouras, N.
|
Reddy, P.
| +6
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2
Investigation of pharmacokinetic drug interaction between clesacostat and DGAT2 inhibitor ervogastat in healthy adult participants
enthalten in:
Clinical and translational science
| 2024
von
Sawant-Basak, A.
|
Bergman, A.
|
Mancuso, J.
| +5
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3
Investigation of pharmacokinetic drug interaction between clesacostat and DGAT2 inhibitor ervogastat in healthy adult participants
enthalten in:
Clinical and Translational Science
| 2024
von
Sawant‐Basak, A.
|
Bergman, A.
|
Mancuso, J.
| +5
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4
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PF‐06817024 in Healthy Participants, Participants with Chronic Rhinosinusitis with Nasal Polyps, and Participants with Atopic Dermatitis : A Phase 1, Randomized, Double‐Blind, Placebo‐Controlled Study
enthalten in:
The Journal of Clinical Pharmacology
| 2024
von
Danto, S.
|
Tsamandouras, N.
|
Reddy, P.
| +6
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5
Investigating CNS distribution of PF-05212377, a P-glycoprotein substrate, by translation of 5-HT6 receptor occupancy from non-human primates to humans
enthalten in:
Biopharmaceutics & drug disposition
| 2023
von
Sawant-Basak, A.
|
Chen, L.
|
Lockwood, P.
| +12
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6
Investigating CNS distribution of PF‐05212377, a P‐glycoprotein substrate, by translation of 5‐HT6 receptor occupancy from non‐human primates to humans
enthalten in:
Biopharmaceutics & Drug Disposition
| 2023
von
Sawant‐Basak, A.
|
Chen, L.
|
Lockwood, P.
| +12
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7
ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty liver disease : two parallel, placebo-controlled, randomized phase 2a trials
enthalten in:
Nature medicine
| 2021
von
Calle, R.
|
Amin, N.
|
Carvajal-Gonzalez, S.
| +18
CommentIn: Nat Rev Endocrinol. 2022 Jan;18(1):2. - PMID 34697464
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8
Efficacy and Safety of PF-06651600 (Ritlecitinib), a Novel JAK3/TEC Inhibitor, in Patients With Moderate-to-Severe Rheumatoid Arthritis and an Inadequate Response to Methotrexate
enthalten in:
Arthritis & rheumatology (Hoboken, N.J.)
| 2020
von
Robinson, M.
|
Damjanov, N.
|
Stamenkovic, B.
| +11
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9
Cancer Immunoprevention : A Case Report Raising the Possibility of "Immuno-interception"
enthalten in:
Cancer prevention research (Philadelphia, Pa.)
| 2020
von
Mancuso, J.
|
Foulkes, W.
|
Pollak, M.
CommentIn: Cancer Prev Res (Phila). 2020 Jun;13(6):493-496. - PMID 32487723
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10
Pharmacokinetic and Pharmacodynamic Effects of a γ-Secretase Modulator, PF-06648671, on CSF Amyloid-β Peptides in Randomized Phase I Studies
enthalten in:
Clinical pharmacology and therapeutics
| 2020
von
Ahn, J.
|
Carrieri, C.
|
Dela Cruz, F.
| +9
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35
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3
Alzheimer's research & therapy
3
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3
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2
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2
Drug metabolism and disposition: the biological...
2
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1
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1
Journal of Alzheimer's disease : JAD
1
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Thema
19
Journal Article
11
Research Support, Non-U.S. Gov't
6
Randomized Controlled Trial
5
Clinical Trial, Phase II
4
Multicenter Study
4
Serotonin
3
5-HT
3
ATP Binding Cassette Transporter, Subfamily B, ...
3
Alzheimer’s Disease
3
Amyloid beta-Peptides
3
Imidazoles
3
Protein Kinase Inhibitors
3
Pyridines
2
Amyloid Precursor Protein Secretases
2
Antibodies, Monoclonal, Humanized
2
CNS
2
Clinical Trial, Phase I
2
DGAT2 protein, human
2
Diacylglycerol O-Acyltransferase
2
EC 1.14.14.1
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Erscheinungszeitraum
12
2020-
17
2010-2019
6
2000-2009
Erscheinungsjahr(e)
Von:
Bis:
Sprache
26
Englisch
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