Suchergebnisse - "Ly, Justin Q"

PubPharm (179)

1

Discovery of TRPA1 Antagonist GDC-6599 : Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease

enthalten in: Journal of medicinal chemistry | 2024

von Terrett, J. | Ly, J. | Katavolos, P. | +53

2

Investigating the Utility of Humanized Pregnane X Receptor-Constitutive Androstane Receptor-CYP3A4/7 Mouse Model to Assess CYP3A-Mediated Induction

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2021

von Ly, J. | Wong, S. | Liu, L. | +3

3

Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists : Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy

enthalten in: Journal of medicinal chemistry | 2021

von Terrett, J. | Chen, H. | Shore, D. | +36

4

A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment

enthalten in: The Journal of experimental medicine | 2021

von Balestrini, A. | Joseph, V. | Dourado, M. | +57

CommentIn: J Exp Med. 2021 Apr 5;218(4):. - PMID 33625497

5

Preclinical Safety Assessment of a Highly Selective and Potent Dual Small-Molecule Inhibitor of CBP/P300 in Rats and Dogs

enthalten in: Toxicologic pathology | 2020

von Katavolos, P. | Cain, G. | Farman, C. | +7

6

Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling

enthalten in: Journal of medicinal chemistry | 2018

von Chen, H. | Volgraf, M. | Do, S. | +27

7

Utility of CYP3A4 and PXR-CAR-CYP3A4/3A7 Transgenic Mouse Models To Assess the Magnitude of CYP3A4 Mediated Drug-Drug Interactions

enthalten in: Molecular pharmaceutics | 2017

von Ly, J. | Messick, K. | Qin, A. | +2

8

Radiological Case: Benign chondroid syringoma

enthalten in: Applied radiology | 2009

von Lowe, J. | Ly, J. | Lusk, J. | +1

9

Anatomic and structural evaluation of the hip : a cross-sectional imaging technique combining anatomic and biomechanical evaluations

enthalten in: Clinical imaging | 2008

von Beall, D. | Martin, H. | Mintz, D. | +4

10

Magnetic resonance imaging findings of golf-related injuries

enthalten in: Current problems in diagnostic radiology | 2008

von Sutcliffe, J. | Ly, J. | Kirby, A. | +1

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