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PubPharm (19)
1
Interplay of Ritonavir-Boosted Oral Cabazitaxel with the Organic Anion-Transporting Polypeptide (OATP) Uptake Transporters and Carboxylesterase 1 in Mice
enthalten in:
Molecular pharmaceutics
| 2024
von
Loos, N.
|
Ferreira Martins, M.
|
Rijmers, J.
| +5
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2
The ABCB1 and ABCG2 efflux transporters limit brain disposition of the SYK inhibitors entospletinib and lanraplenib
enthalten in:
Toxicology and applied pharmacology
| 2024
von
Loos, N.
|
Sparidans, R.
|
Heydari, P.
| +4
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3
Impact of loperamide on the pharmacokinetics and tissue disposition of ritonavir-boosted oral docetaxel therapy; a preclinical assessment
enthalten in:
Cancer chemotherapy and pharmacology
| 2024
von
Loos, N.
|
Bui, V.
|
de Jong, D.
| +4
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4
Coadministration of ABCB1/P-glycoprotein inhibitor elacridar improves tissue distribution of ritonavir-boosted oral cabazitaxel in mice
enthalten in:
International journal of pharmaceutics
| 2024
von
Loos, N.
|
Martins, M.
|
de Jong, D.
| +4
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5
Development and validation of an HPLC-MS/MS method to quantify the KRAS inhibitor adagrasib in mouse plasma and tissue-related matrices
enthalten in:
Biomedical chromatography : BMC
| 2023
von
Retmana, I.
|
Loos, N.
|
Schinkel, A.
| +2
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6
Validated LC-MS/MS method for simultaneous quantification of KRASG12C inhibitor sotorasib and its major circulating metabolite (M24) in mouse matrices and its application in a mouse pharmacokinetic study
enthalten in:
Journal of pharmaceutical and biomedical analysis
| 2023
von
Retmana, I.
|
Loos, N.
|
Schinkel, A.
| +2
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7
Pharmacokinetics of the KRASG12C inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c
enthalten in:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
| 2023
von
Loos, N.
|
Retmana, I.
|
Rijmers, J.
| +6
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8
P-glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Main Active Heroin Metabolites 6-monoacetylmorphine (6-MAM) and Morphine in Mice
enthalten in:
Pharmaceutical research
| 2023
von
F Martins, M.
|
Loos, N.
|
El Yattouti, M.
| +6
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9
The inhibitory and inducing effects of ritonavir on hepatic and intestinal CYP3A and other drug-handling proteins
enthalten in:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
| 2023
von
Loos, N.
|
Beijnen, J.
|
Schinkel, A.
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10
P-glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Main Active Heroin Metabolites 6-monoacetylmorphine (6-MAM) and Morphine in Mice
enthalten in:
Pharmaceutical research
| 2023
von
F. Martins, M.
|
Loos, N.
|
el Yattouti, M.
| +6
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Thema
15
Journal Article
8
Cytochrome P-450 CYP3A
8
EC 1.14.14.1
6
P-glycoprotein/ABCB1
6
Ritonavir
5
ATP Binding Cassette Transporter, Subfamily B
5
BCRP/ABCG2
5
O3J8G9O825
4
6-monoacetylmorphine/6-MAM
4
ATP Binding Cassette Transporter, Subfamily B, ...
4
EC 3.6.5.2
4
Pharmacokinetics
4
Proto-Oncogene Proteins p21(ras)
4
heroin/diacetylmorphine
4
morphine
3
2B2VM6UC8G
3
51F690397J
3
ABCB1 protein, human
3
ABCB1/P-glycoprotein
3
ABCG2/Breast cancer resistance protein
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Erscheinungszeitraum
4
2024
10
2023
3
2022
2
2021
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Englisch
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