Suchergebnisse - "Ling, Yun"

PubPharm (45)

1

Discovery of N-(2-chloro-5-(3-(pyridin-4-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide (FD274) as a highly potent PI3K/mTOR dual inhibitor for the treatment of acute myeloid leukemia

enthalten in: European journal of medicinal chemistry | 2023

von Yang, C. | Chen, Y. | Wu, T. | +8

2

Discovery of a high potent PIM kinase inhibitor for acute myeloid leukemia based on N-pyridinyl amide scaffold by optimizing the fragments toward to Lys67 and Asp128/Glu171

enthalten in: European journal of medicinal chemistry | 2023

von Xiang, R. | Lu, M. | Wu, T. | +9

3

P38-DAPK1 axis regulated LC3-associated phagocytosis (LAP) of microglia in an in vitro subarachnoid hemorrhage model

enthalten in: Cell communication and signaling : CCS | 2023

von Chen, X. | Tao, T. | Liu, X. | +15

4

An inhibitor with GSK3β and DYRK1A dual inhibitory properties reduces Tau hyperphosphorylation and ameliorates disease in models of Alzheimer's disease

enthalten in: Neuropharmacology | 2023

von Liu, X. | Lai, L. | Chen, J. | +13

5

Neurokinin-1 receptor drives PKCɑ-AURKA/N-Myc signaling to facilitate the neuroendocrine progression of prostate cancer

enthalten in: Cell death & disease | 2023

von Zhang, X. | Li, J. | Li, L. | +10

6

Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia

enthalten in: The Journal of experimental medicine | 2023

von García-García, A. | Pérez de Diego, R. | Flores, C. | +154

CommentIn: Transplantation. 2023 Oct 1;107(10):2084-2086. - PMID 37749810

7

Increased Anxiety-like Behaviors in Adgra1-/- Male But Not Female Mice are Attributable to Elevated Neuron Dendrite Density, Upregulated PSD95 Expression, and Abnormal Activation of the PI3K/AKT/GSK-3β and MEK/ERK Pathways

enthalten in: Neuroscience | 2022

von Zhang, X. | Shen, C. | Wang, X. | +9

8

POLE2 facilitates the malignant phenotypes of glioblastoma through promoting AURKA-mediated stabilization of FOXM1

enthalten in: Cell death & disease | 2022

von Zhang, P. | Chen, X. | Zhang, L. | +4

9

A pyridinesulfonamide derivative FD268 suppresses cell proliferation and induces apoptosis via inhibiting PI3K pathway in acute myeloid leukemia

enthalten in: PloS one | 2022

von Chen, Y. | Wu, T. | Yang, C. | +10

10

Bioisosteric replacements of the indole moiety for the development of a potent and selective PI3Kδ inhibitor : Design, synthesis and biological evaluation

enthalten in: European journal of medicinal chemistry | 2021

von Yang, C. | Xu, C. | Li, Z. | +12

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