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PubPharm (74)
21
Evaluation ofin vitroabsorption, distribution, metabolism, and excretion and assessment of drug-drug interaction of rucaparib, an orally potent poly(ADP-ribose) polymerase inhibitor
enthalten in:
Xenobiotica
| 2020
von
Liao, M.
|
Jaw-Tsai, S.
|
Beltman, J.
| +3
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22
Positron Emission Tomography Imaging of [11 C]Rosuvastatin Hepatic Concentrations and Hepatobiliary Transport in Humans in the Absence and Presence of Cyclosporin A
enthalten in:
Clinical pharmacology and therapeutics
| 2019
von
Billington, S.
|
Shoner, S.
|
Lee, S.
| +17
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23
Comparison of uptake transporter functions in hepatocytes in different species to determine the optimal model for evaluating drug transporter activities in humans
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2019
von
Liao, M.
|
Zhu, Q.
|
Zhu, A.
| +6
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24
Evaluation of absorption, distribution, metabolism, and excretion of [14C]-rucaparib, a poly(ADP-ribose) polymerase inhibitor, in patients with advanced solid tumors
enthalten in:
Investigational new drugs
| 2019
von
Liao, M.
|
Watkins, S.
|
Nash, E.
| +10
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25
Evaluation of absorption, distribution, metabolism, and excretion of [14C]-rucaparib, a poly(ADP-ribose) polymerase inhibitor, in patients with advanced solid tumors
enthalten in:
Investigational new drugs
| 2019
von
Liao, M.
|
Watkins, S.
|
Nash, E.
| +10
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26
Evaluation of absorption, distribution, metabolism, and excretion of [14C]-rucaparib, a poly(ADP-ribose) polymerase inhibitor, in patients with advanced solid tumors
enthalten in:
Investigational new drugs
| 2019
von
Liao, M.
|
Watkins, S.
|
Nash, E.
| +10
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27
A Comparison of Total and Plasma Membrane Abundance of Transporters in Suspended, Plated, Sandwich-Cultured Human Hepatocytes Versus Human Liver Tissue Using Quantitative Targeted Proteomics and Cell Surface Biotinylation
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2019
von
Kumar, V.
|
Salphati, L.
|
Hop, C.
| +8
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28
Comparison of uptake transporter functions in hepatocytes in different species to determine the optimal model for evaluating drug transporter activities in humans
enthalten in:
Xenobiotica
| 2019
von
Liao, M.
|
Zhu, Q.
|
Zhu, A.
| +6
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29
Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation : Perspectives From the International Transporter Consortium
enthalten in:
Clinical pharmacology and therapeutics
| 2018
von
Chu, X.
|
Liao, M.
|
Shen, H.
| +13
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30
Efflux transporter breast cancer resistance protein dominantly expresses on the membrane of red blood cells, hinders partitioning of its substrates into the cells, and alters drug-drug interaction profiles
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2018
von
Shi, P.
|
Liao, M.
|
Chuang, B.
| +7
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36
Journal Article
12
Rucaparib
10
Research Support, Non-U.S. Gov't
9
BCRP
9
Research Support, N.I.H., Extramural
8
Pharmacokinetics
7
ATP Binding Cassette Transporter, Subfamily G, ...
7
EC 1.14.14.1
6
9035-51-2
6
Cytochrome P-450 Enzyme System
6
Membrane Transport Proteins
6
PARP inhibitor
6
rucaparib
5
8237F3U7EH
5
Antineoplastic Agents
5
Cytochrome P-450 CYP3A
5
Indoles
5
Neoplasm Proteins
5
Review
4
83MVU38M7Q
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Erscheinungszeitraum
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2020-
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2010-2019
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2000-2009
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